Pre_GI: BLASTN Hits

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Query: NC_004741:2456297 Shigella flexneri 2a str. 2457T, complete genome

Start: 2456297, End: 2479599, Length: 23303

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a highly virulent strain that has been widely used for genetic and clinical research. Causes enteric disease. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_004337:24784612478461250482826368Shigella flexneri 2a str. 301, complete genome036170BLASTN svgBLASTP svg
NC_008258:24730002473000249769824699Shigella flexneri 5 str. 8401, complete genome034660BLASTN svgBLASTP svg
CU928160:25130002513000253520022201Escherichia coli IAI1 chromosome, complete genome033670BLASTN svgBLASTP svg
NC_007384:25878762587876261159923724Shigella sonnei Ss046, complete genome033570BLASTN svgBLASTP svg
CP002185:26596282659628268309923472Escherichia coli W, complete genome033530BLASTN svgBLASTP svg
AP010958:2911741*2911741294759935859Escherichia coli O103:H2 str. 12009 DNA, complete genome033500BLASTN svgBLASTP svg
NC_009801:26397872639787266007120285Escherichia coli E24377A, complete genome033300BLASTN svgBLASTP svg
CU928145:27085002708500272609917600Escherichia coli 55989 chromosome, complete genome033050BLASTN svgBLASTP svg
NC_011748:27085002708500272609917600Escherichia coli 55989, complete genome033050BLASTN svgBLASTP svg
NC_011751:27688642768864278709918236Escherichia coli UMN026 chromosome, complete genome031030BLASTN svgBLASTP svg
NC_008253:24997352499735251999320259Escherichia coli 536, complete genome030170BLASTN svgBLASTP svg
NC_009800:2505872*2505872252809922228Escherichia coli HS, complete genome027940BLASTN svgBLASTP svg
NC_010468:14127911412791143188119091Escherichia coli ATCC 8739, complete genome027610BLASTN svgBLASTP svg
CP002516:14194131419413144219622784Escherichia coli KO11, complete genome027570BLASTN svgBLASTP svg
NC_007613:2376974*2376974240022423251Shigella boydii Sb227, complete genome026920BLASTN svgBLASTP svg
NC_010658:2529033*2529033255581226780Shigella boydii CDC 3083-94, complete genome026790BLASTN svgBLASTP svg
NC_008563:26104992610499263209921601Escherichia coli APEC O1, complete genome025550BLASTN svgBLASTP svg
NC_010473:2548946*2548946258173732792Escherichia coli str. K-12 substr. DH10B, complete genome024210BLASTN svgBLASTP svg
NC_002695:3189425*3189425321610426680Escherichia coli O157:H7 str. Sakai, complete genome021150BLASTN svgBLASTP svg
NC_010498:25557062555706258100625301Escherichia coli SMS-3-5, complete genome019400BLASTN svgBLASTP svg
NC_011750:2585015*2585015261198826974Escherichia coli IAI39 chromosome, complete genome019300BLASTN svgBLASTP svg
NC_004431:27472372747237277257425338Escherichia coli CFT073, complete genome018780BLASTN svgBLASTP svg
NC_002655:3260500*3260500328246521966Escherichia coli O157:H7 EDL933, complete genome015090BLASTN svgBLASTP svg
NC_007946:26254612625461264923523775Escherichia coli UTI89, complete genome014780BLASTN svgBLASTP svg
NC_007606:23530982353098237552222425Shigella dysenteriae Sd197, complete genome014220BLASTN svgBLASTP svg
CP002797:24729082472908249359920692Escherichia coli NA114, complete genome09969BLASTN svgBLASTP svg
NC_000913:2455037*2455037248136126325Escherichia coli K12, complete genome07967BLASTN svgBLASTP svg
AC_000091:24624612462461248878526325Escherichia coli W3110 DNA, complete genome07967BLASTN svgBLASTP svg
NC_007606:4182188*4182188420162219435Shigella dysenteriae Sd197, complete genome07571BLASTN svgBLASTP svg
NC_011750:43900004390000444275952760Escherichia coli IAI39 chromosome, complete genome02686BLASTN svgBLASTP svg
AC_000091:4501430*4501430452291521486Escherichia coli W3110 DNA, complete genome01154BLASTN svgBLASTP svg
NC_000913:44947734494773451470019928Escherichia coli K12, complete genome01154BLASTN svgBLASTP svg
NC_010473:4596500*4596500461806621567Escherichia coli str. K-12 substr. DH10B, complete genome01154BLASTN svgBLASTP svg
NC_011751:49925004992500501338720888Escherichia coli UMN026 chromosome, complete genome01154BLASTN svgBLASTP svg
NC_007384:40950164095016412229027275Shigella sonnei Ss046, complete genome01150BLASTN svgBLASTP svg
NC_007384:16968311696831171856121731Shigella sonnei Ss046, complete genome01150BLASTN svgBLASTP svg
NC_004431:35131473513147354268029534Escherichia coli CFT073, complete genome01150BLASTN svgBLASTP svg
NC_004337:3590323*35903233952993362671Shigella flexneri 2a str. 301, complete genome01150BLASTN svgBLASTP svg
NC_004741:41320564132056415578223727Shigella flexneri 2a str. 2457T, complete genome01142BLASTN svgBLASTP svg
NC_008258:26980626980629518525380Shigella flexneri 5 str. 8401, complete genome01134BLASTN svgBLASTP svg
NC_004337:36219853621985364626824284Shigella flexneri 2a str. 301, complete genome01126BLASTN svgBLASTP svg
NC_014121:37769023776902380024423343Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete0954BLASTN svgBLASTP svg
NC_007613:41197714119771413859918829Shigella boydii Sb227, complete genome0932BLASTN svgBLASTP svg
NC_003198:2453074*2453074247785124778Salmonella enterica subsp. enterica serovar Typhi str. CT18,0837BLASTN svgBLASTP svg
NC_008258:18738051873805189655222748Shigella flexneri 5 str. 8401, complete genome0702BLASTN svgBLASTP svg
NC_004851:19170919170922249930791Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence0702BLASTN svgBLASTP svg
NC_004741:4364235*4364235438964325409Shigella flexneri 2a str. 2457T, complete genome0702BLASTN svgBLASTP svg
NC_004337:4374500*4374500439909924600Shigella flexneri 2a str. 301, complete genome0702BLASTN svgBLASTP svg
NC_007613:10380001038000106059922600Shigella boydii Sb227, complete genome0654BLASTN svgBLASTP svg
NC_010658:36226103622610364133018721Shigella boydii CDC 3083-94, complete genome6e-180638BLASTN svgBLASTP svg
NC_010660:33109331095109917991Shigella boydii CDC 3083-94 plasmid pBS512_211, complete sequence4e-178632BLASTN svgBLASTP svg
NC_007613:76123476123478018918956Shigella boydii Sb227, complete genome1e-177630BLASTN svgBLASTP svg
NC_007613:44030704403070442929526226Shigella boydii Sb227, complete genome1e-177630BLASTN svgBLASTP svg
NC_007608:970929709212311926028Shigella boydii Sb227 plasmid pSB4_227, complete sequence1e-177630BLASTN svgBLASTP svg
NC_007613:34703143470314350909338780Shigella boydii Sb227, complete genome4e-175622BLASTN svgBLASTP svg
NC_007606:12091321209132122967220541Shigella dysenteriae Sd197, complete genome1e-171611BLASTN svgBLASTP svg
NC_008253:28285732828573285250723935Escherichia coli 536, complete genome1e-168601BLASTN svgBLASTP svg
NC_008253:3122148*3122148315923237085Escherichia coli 536, complete genome3e-166593BLASTN svgBLASTP svg
NC_008253:3941938*3941938399883856901Escherichia coli 536, complete genome3e-166593BLASTN svgBLASTP svg
NC_004431:4270305*4270305431798947685Escherichia coli CFT073, complete genome1e-153551BLASTN svgBLASTP svg
NC_008563:47393334739333476356524233Escherichia coli APEC O1, complete genome7e-152545BLASTN svgBLASTP svg
NC_012917:32411963241196329451553320Pectobacterium carotovorum subsp. carotovorum PC1, complete genome7e-149535BLASTN svgBLASTP svg
NC_014121:4299500*4299500433477235273Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete2e-142513BLASTN svgBLASTP svg
NC_014121:36275883627588367459947012Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete2e-142513BLASTN svgBLASTP svg
NC_014121:23304512330451236009929649Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete2e-142513BLASTN svgBLASTP svg
NC_014121:48950048950052159932100Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete4e-138500BLASTN svgBLASTP svg
NC_010067:4418000*4418000444281924820Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete1e-134488BLASTN svgBLASTP svg
NC_004631:38096783809678383452924852Salmonella enterica subsp. enterica serovar Typhi Ty2, complete2e-121444BLASTN svgBLASTP svg
NC_003198:38241873824187384903924853Salmonella enterica subsp. enterica serovar Typhi str. CT18,2e-121444BLASTN svgBLASTP svg
NC_006905:39427533942753396819425442Salmonella enterica subsp. enterica serovar Choleraesuis str2e-118434BLASTN svgBLASTP svg
NC_015963:11717811717814980332626Enterobacter asburiae LF7a plasmid pENTAS01, complete sequence6e-109402BLASTN svgBLASTP svg
NC_012214:1117325*1117325114343626112Erwinia pyrifoliae Ep1/96, complete genome2e-106394BLASTN svgBLASTP svg
NC_012214:12126161212616123625023635Erwinia pyrifoliae Ep1/96, complete genome2e-106394BLASTN svgBLASTP svg
NC_012214:13555001355500137677021271Erwinia pyrifoliae Ep1/96, complete genome2e-106394BLASTN svgBLASTP svg
NC_012214:2805297*2805297283239127095Erwinia pyrifoliae Ep1/96, complete genome2e-106394BLASTN svgBLASTP svg
NC_010498:10940001094000111633222333Escherichia coli SMS-3-5, complete genome4e-101377BLASTN svgBLASTP svg
NC_006905:28576992857699289909341395Salmonella enterica subsp. enterica serovar Choleraesuis str2e-99371BLASTN svgBLASTP svg
AP010958:2455052*2455052247359918548Escherichia coli O103:H2 str. 12009 DNA, complete genome9e-99369BLASTN svgBLASTP svg
NC_011740:28599332859933288499725065Escherichia fergusonii ATCC 35469, complete genome8e-90339BLASTN svgBLASTP svg
NC_010067:24881412488141251937331233Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete3e-89337BLASTN svgBLASTP svg
NC_010694:10527221052722108466031939Erwinia tasmaniensis, complete genome5e-85323BLASTN svgBLASTP svg
NC_007613:15330241533024155939726374Shigella boydii Sb227, complete genome3e-77297BLASTN svgBLASTP svg
NC_013716:357928*35792840652048593Citrobacter rodentium ICC168, complete genome8e-50206BLASTN svgBLASTP svg
NC_011750:4947500*4947500496714419645Escherichia coli IAI39 chromosome, complete genome5e-48200BLASTN svgBLASTP svg
NC_015968:33019583301958333436632409Enterobacter asburiae LF7a chromosome, complete genome1e-45192BLASTN svgBLASTP svg
CP002797:4603787*4603787464340739621Escherichia coli NA114, complete genome1e-45192BLASTN svgBLASTP svg
NC_013716:50202045020204504905228849Citrobacter rodentium ICC168, complete genome3e-43184BLASTN svgBLASTP svg
NC_008253:47354184735418477925943842Escherichia coli 536, complete genome2e-25125BLASTN svgBLASTP svg
NC_004337:25482882548288256963421347Shigella flexneri 2a str. 301, complete genome2e-22115BLASTN svgBLASTP svg
NC_004741:25264212526421254776721347Shigella flexneri 2a str. 2457T, complete genome2e-22115BLASTN svgBLASTP svg
NC_008258:25428632542863256544822586Shigella flexneri 5 str. 8401, complete genome2e-22115BLASTN svgBLASTP svg
NC_013850:33035003303500332954126042Klebsiella variicola At-22 chromosome, complete genome5e-20107BLASTN svgBLASTP svg
NC_014306:31020003102000312424122242Erwinia billingiae Eb661, complete genome5e-20107BLASTN svgBLASTP svg
NC_014306:35249803524980358375158772Erwinia billingiae Eb661, complete genome5e-20107BLASTN svgBLASTP svg
NC_014306:49013904901390494640145012Erwinia billingiae Eb661, complete genome5e-20107BLASTN svgBLASTP svg
NC_008258:4345400*4345400436989824499Shigella flexneri 5 str. 8401, complete genome2e-19105BLASTN svgBLASTP svg
NC_011751:34536833453683351238358701Escherichia coli UMN026 chromosome, complete genome8e-19103BLASTN svgBLASTP svg
NC_004547:843475*84347586442120947Erwinia carotovora subsp. atroseptica SCRI1043, complete genome3e-18101BLASTN svgBLASTP svg
CP002797:47757804775780479609920320Escherichia coli NA114, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_013961:73037*7303710749134455Erwinia amylovora, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_014800:32986132986135277422914Pseudoalteromonas sp. SM9913 chromosome chromosome II, complete1e-1489.7BLASTN svgBLASTP svg
NC_010067:51000510007450923510Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete1e-1489.7BLASTN svgBLASTP svg
NC_010694:12508411250841127452923689Erwinia tasmaniensis, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_010067:1300606*1300606132180421199Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete7e-1383.8BLASTN svgBLASTP svg
NC_004431:3409389*3409389349493685548Escherichia coli CFT073, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_008739:41793417936534823556Marinobacter aquaeolei VT8 plasmid pMAQU02, complete sequence1e-1179.8BLASTN svgBLASTP svg
NC_008740:443274*44327451891675643Marinobacter aquaeolei VT8, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_011750:10940001094000111509921100Escherichia coli IAI39 chromosome, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_010498:301000*30100034338442385Escherichia coli SMS-3-5, complete genome7e-1073.8BLASTN svgBLASTP svg
AP010958:36695003669500372827458775Escherichia coli O103:H2 str. 12009 DNA, complete genome3e-0971.9BLASTN svgBLASTP svg
CU928145:2973968*2973968299959925632Escherichia coli 55989 chromosome, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_002505:514732*51473255228437553Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, complete3e-0971.9BLASTN svgBLASTP svg
NC_008345:37569773756977377563418658Shewanella frigidimarina NCIMB 400, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_010488:48868488687267123804Escherichia coli SMS-3-5 plasmid pSMS35_130, complete sequence3e-0971.9BLASTN svgBLASTP svg
NC_011748:2973968*2973968299959925632Escherichia coli 55989, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_020063:4127161*4127161415360026440Enterobacteriaceae bacterium strain FGI 57, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_004459:349500*34950040074451245Vibrio vulnificus CMCP6 chromosome I, complete sequence1e-0869.9BLASTN svgBLASTP svg
NC_009648:38036223803622385072747106Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_009997:26996442699644272218322540Shewanella baltica OS195, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_009999:38832388326239723566Shewanella baltica OS195 plasmid pS19502, complete sequence4e-0867.9BLASTN svgBLASTP svg
NC_011740:18318451831845185021818374Escherichia fergusonii ATCC 35469, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_015566:2125403*2125403214809922697Serratia sp. AS12 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_015567:2125415*2125415214809922685Serratia sp. AS9 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_015065:16231716231720800945693Acidobacterium sp. MP5ACTX9 plasmid pACIX902, complete sequence2e-0765.9BLASTN svgBLASTP svg
NC_015061:3840463*3840463391463974177Rahnella sp. Y9602 chromosome, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_009790:42112421126914727036Escherichia coli E24377A plasmid pETEC_74, complete sequence7e-0763.9BLASTN svgBLASTP svg
NC_013716:44082014408201443527827078Citrobacter rodentium ICC168, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_012779:3176820*3176820323178054961Edwardsiella ictaluri 93-146, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_009997:51882215188221522795839738Shewanella baltica OS195, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_009512:469000*46900049317124172Pseudomonas putida F1, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_002506:82240182240184494222542Vibrio cholerae O1 biovar eltor str. N16961 chromosome II, complete3e-0661.9BLASTN svgBLASTP svg