Pre_GI Gene

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Host: NC_002506 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002506:822401 Vibrio cholerae O1 biovar eltor str. N16961 chromosome II, complete

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This is an epidemic serogroup of Vibrio cholerae isolated in 1971 in Bangladesh and is distinguished from the classical biotype due to hemolysin production. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8224018238221422transcriptional regulator GntR familyQuickGO ontologyBLASTP
8239518255431593cytochrome d ubiquinol oxidase subunit IQuickGO ontologyBLASTP
8255568266921137cytochrome d ubiquinol oxidase subunit IIQuickGO ontologyBLASTP
827514827717204hypothetical proteinBLASTP
8279348292591326D-serine dehydrataseQuickGO ontologyBLASTP
829467830411945D-serine deaminase activatorQuickGO ontologyBLASTP
8307118317871077hydrolase putativeQuickGO ontologyBLASTP
831895832056162integrase-related proteinQuickGO ontologyBLASTP
832585832740156hypothetical proteinBLASTP
832685833065381hypothetical proteinBLASTP
833090833485396hypothetical proteinBLASTP
8334978345611065hypothetical proteinBLASTP
8345748356831110hypothetical proteinBLASTP
8357348367951062hypothetical proteinBLASTP
8378928389231032L-threonine 3-dehydrogenaseQuickGO ontologyBLASTP
83892684011911942-amino-3-ketobutyrate coenzyme A ligaseQuickGO ontologyBLASTP
841276842037762transcriptional regulator LuxR familyQuickGO ontologyBLASTP
842137843075939transcriptional regulator LysR familyQuickGO ontologyBLASTP
843069843452384glyoxylase I family proteinQuickGO ontologyBLASTP
8435308449421413hypothetical proteinBLASTP