Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:3809678 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
380967838108621185hypothetical proteinBLASTP
381085238134042553trimethylamine-N-oxide reductase precursorQuickGO ontologyBLASTP
38133973814029633chaperone protein TorDQuickGO ontologyBLASTP
381421938156191401probable cytochrome c peroxidaseQuickGO ontologyBLASTP
38156253816242618heme exporter protein A2QuickGO ontologyBLASTP
38162393816898660heme exporter protein B2QuickGO ontologyBLASTP
38169413817687747heme exporter protein C2QuickGO ontologyBLASTP
38176843817896213heme exporter protein D2QuickGO ontologyBLASTP
38178933818372480cytochrome c-type biogenesis protein E2QuickGO ontologyBLASTP
381836938203001932cytochrome c-type biogenesis protein F2QuickGO ontologyBLASTP
38202973820854558thioldisulfide interchange proteinQuickGO ontologyBLASTP
382085138218941044cytochrome c-type biogenesis protein H2QuickGO ontologyBLASTP
382201638232421227putative ATPGTP-binding proteinQuickGO ontologyBLASTP
38232443823579336putative lipoproteinQuickGO ontologyBLASTP
38238863824299414heat shock protein AQuickGO ontologyBLASTP
38244093824837429heat shock protein BQuickGO ontologyBLASTP
382503138266921662hypothetical proteinBLASTP
38274723827834363hypothetical proteinBLASTP
38278313828361531hypothetical proteinBLASTP
382844338297651323D-serine dehydrataseQuickGO ontologyBLASTP
382978338311201338DsdX permeaseQuickGO ontologyBLASTP
38313463832269924D-serine deaminase activatorQuickGO ontologyBLASTP
383233338334181086hypothetical proteinBLASTP
383334538345291185multidrug resistance protein DQuickGO ontologyBLASTP