Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS




NC_012563: Clostridium botulinum A2 str. Kyoto, complete genome

NCBI: NC_012563

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
11*1946419464Island text6.3324422.352544.2132Neighbours21BLASTN1.gbk
236000*7859942600Island text5.9872223.141542.8304Neighbours21BLASTN+IslandViewer 36000.gbk
3122000*14417822179Island text4.8956319.505133.6467Neighbours21BLASTN122000.gbk
4519037*54582126785Island text4.4849622.117840.755Neighbours21BLASTN+519037.gbk
581199383064718655Island text6.5184818.172423.8133Neighbours21BLASTNIslandViewer 811993.gbk
61348500136732318824Island text3.5784117.929225.2832Neighbours21BLASTN+1348500.gbk
71464000148609922100Island text3.0589118.004935.1212Neighbours21BLASTN1464000.gbk
81681639170433322695Island text5.0154217.929137.2264Neighbours21BLASTN+IslandViewer 1681639.gbk
91704345173190427560Island text3.0715717.649634.5596Neighbours21BLASTN+1704345.gbk
102101449212008818640Island text2.5824918.099535.4063Neighbours21BLASTN+2101449.gbk
112203037222476521729Island text2.6274818.199232.9714Neighbours21BLASTN+2203037.gbk
122230403*225235521953Island text1.9981420.547928.2535Neighbours21BLASTN+IslandViewer 2230403.gbk
132384500240296118462Island text2.084318.114727.5003Neighbours21BLASTN2384500.gbk
142466000248852922530Island text2.4622816.992934.1576Neighbours21BLASTN2466000.gbk
152566500258437417875Island text3.2623318.199835.6316Neighbours21BLASTN+IslandViewer 2566500.gbk
162597934261595118018Island text4.4884918.436938.3786Neighbours21BLASTN+2597934.gbk
172680246*272077540530Island text2.8308718.595836.5715Neighbours21BLASTN+2680246.gbk
182721658*274175820101Island text2.9481818.266735.4327Neighbours21BLASTN2721658.gbk
192761570*280230240733Island text3.058118.470133.605Neighbours21BLASTN+2761570.gbk
202925472296409938628Island text4.3850618.548633.3917Neighbours21BLASTN+2925472.gbk
212979147300249023344Island text2.1529118.321433.5242Neighbours21BLASTN2979147.gbk
223090954312052229569Island text3.2012318.035336.2535Neighbours21BLASTN3090954.gbk
233288124330917721054Island text2.4634118.123830.0707Neighbours21BLASTN3288124.gbk
243374904*339859023687Island text3.8671618.596336.491Neighbours21BLASTN3374904.gbk
253416509*343524718739Island text2.2856718.002227.1227Neighbours21BLASTN3416509.gbk
263556763*357533918577Island text3.3921917.859336.9107Neighbours21BLASTN3556763.gbk
273580000*360253222533Island text1.9273416.281632.6227Neighbours21BLASTN+3580000.gbk
283729817376659036774Island text2.5358917.824534.1551Neighbours21BLASTN+3729817.gbk
293921859394111319255Island text2.3606818.546931.7076Neighbours21BLASTN3921859.gbk
303956500*399649139992Island text3.841521.07640.1787Neighbours21BLASTN+3956500.gbk
314004709*403727332565Island text4.4752121.619440.8068Neighbours21BLASTNIslandViewer 4004709.gbk
324101000*412265321654Island text2.6348918.847336.2384Neighbours21BLASTN4101000.gbk