Pre_GI: BLASTN Hits

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Query: NC_012563:1681639 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 1681639, End: 1704333, Length: 22695

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:2676746*2676746271365836913Clostridium botulinum B1 str. Okra, complete genome01247BLASTN svgBLASTP svg
NC_010418:18813818813820879920662Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete2e-72281BLASTN svgBLASTP svg
NC_020291:11222821122282114131119030Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome7e-44186BLASTN svgBLASTP svg
NC_021182:33842833842836240623979Clostridium pasteurianum BC1, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_010674:95027695027696907618801Clostridium botulinum B str. Eklund 17B, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_012563:29254722925472296409938628Clostridium botulinum A2 str. Kyoto, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_021182:30041530041531873118317Clostridium pasteurianum BC1, complete genome3e-0661.9BLASTN svgBLASTP svg