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Query: NC_012563:2680246 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 2680246, End: 2720775, Length: 40530

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:2511035*2511035254588934855Clostridium botulinum B1 str. Okra, complete genome04950BLASTN svgBLASTP svg
NC_010520:2585014*2585014262041935406Clostridium botulinum A3 str. Loch Maree, complete genome04698BLASTN svgBLASTP svg
NC_014328:1405484*1405484142841522932Clostridium ljungdahlii ATCC 49587 chromosome, complete genome2e-141511BLASTN svgBLASTP svg
NC_008261:2157713*2157713217590318191Clostridium perfringens ATCC 13124, complete genome1e-136496BLASTN svgBLASTP svg
NC_008262:1835613*1835613185504319431Clostridium perfringens SM101, complete genome2e-134488BLASTN svgBLASTP svg
NC_020291:1464500*1464500148221117712Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-81311BLASTN svgBLASTP svg
NC_010520:15860001586000160832222323Clostridium botulinum A3 str. Loch Maree, complete genome3e-75291BLASTN svgBLASTP svg
NC_010516:35931035931038266123352Clostridium botulinum B1 str. Okra, complete genome3e-75291BLASTN svgBLASTP svg
NC_003366:2057656*2057656208209924444Clostridium perfringens str. 13, complete genome2e-42182BLASTN svgBLASTP svg
NC_012563:519037*51903754582126785Clostridium botulinum A2 str. Kyoto, complete genome4e-31145BLASTN svgBLASTP svg
NC_010520:496500*49650051930622807Clostridium botulinum A3 str. Loch Maree, complete genome1e-28137BLASTN svgBLASTP svg
NC_008262:1950205*1950205196967819474Clostridium perfringens SM101, complete genome2e-27133BLASTN svgBLASTP svg
NC_010516:23740002374000239681422815Clostridium botulinum B1 str. Okra, complete genome2e-24123BLASTN svgBLASTP svg
NC_014964:11699251169925118860418680Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete4e-22115BLASTN svgBLASTP svg
NC_014538:1311500*1311500133539723898Thermoanaerobacter sp. X513 chromosome, complete genome4e-22115BLASTN svgBLASTP svg
NC_014393:93700093700097266735668Clostridium cellulovorans 743B chromosome, complete genome2e-20109BLASTN svgBLASTP svg
NC_010520:72531272531274947124160Clostridium botulinum A3 str. Loch Maree, complete genome9e-20107BLASTN svgBLASTP svg
NC_008346:14310511431051145644725397Syntrophomonas wolfei subsp. wolfei str. Goettingen, complete4e-19105BLASTN svgBLASTP svg
NC_010516:514000*51400053623322234Clostridium botulinum B1 str. Okra, complete genome2e-1799.6BLASTN svgBLASTP svg
NC_015913:11796611796615176933804Candidatus Arthromitus sp. SFB-mouse-Japan, complete genome1e-1593.7BLASTN svgBLASTP svg
NC_010674:24352412435241245936424124Clostridium botulinum B str. Eklund 17B, complete genome5e-1591.7BLASTN svgBLASTP svg
NC_011653:1463743*1463743148807524333Thermosipho africanus TCF52B, complete genome8e-1487.7BLASTN svgBLASTP svg
NC_019970:1343670*1343670136621022541Thermoanaerobacterium thermosaccharolyticum M0795, complete genome8e-1487.7BLASTN svgBLASTP svg
NC_014657:944000*94400096534721348Caldicellulosiruptor owensensis OL chromosome, complete genome1e-1283.8BLASTN svgBLASTP svg
NC_013216:3376186*3376186339624020055Desulfotomaculum acetoxidans DSM 771, complete genome1e-1283.8BLASTN svgBLASTP svg
NC_011661:1175743*1175743119876723025Dictyoglomus turgidum DSM 6724, complete genome1e-1283.8BLASTN svgBLASTP svg
NC_011898:35677613567761360080233042Clostridium cellulolyticum H10, complete genome5e-1281.8BLASTN svgBLASTP svg
NC_010516:23282882328288235225123964Clostridium botulinum B1 str. Okra, complete genome2e-1179.8BLASTN svgBLASTP svg
NC_010336:733751*73375175293719187Francisella philomiragia subsp. philomiragia ATCC 25017, complete8e-1177.8BLASTN svgBLASTP svg
NC_011296:1299388*1299388132999530608Thermodesulfovibrio yellowstonii DSM 11347, complete genome3e-1075.8BLASTN svgBLASTP svg
NC_013517:14803681480368150126620899Sebaldella termitidis ATCC 33386, complete genome1e-0973.8BLASTN svgBLASTP svg
NC_011772:3787500*3787500381637528876Bacillus cereus G9842, complete genome2e-0869.9BLASTN svgBLASTP svg
NC_012121:897866*89786692042622561Staphylococcus carnosus subsp. carnosus TM300, complete genome8e-0867.9BLASTN svgBLASTP svg
NC_021182:554000*55400058588731888Clostridium pasteurianum BC1, complete genome8e-0867.9BLASTN svgBLASTP svg
NC_013515:347671*34767139636648696Streptobacillus moniliformis DSM 12112, complete genome3e-0765.9BLASTN svgBLASTP svg
NC_012563:37298173729817376659036774Clostridium botulinum A2 str. Kyoto, complete genome3e-0765.9BLASTN svgBLASTP svg
NC_004722:3777907*3777907379634818442Bacillus cereus ATCC 14579, complete genome3e-0765.9BLASTN svgBLASTP svg
NC_003909:3587695*3587695360609918405Bacillus cereus ATCC 10987, complete genome3e-0765.9BLASTN svgBLASTP svg
NC_003454:983681*983681100260518925Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete1e-0663.9BLASTN svgBLASTP svg
NC_015558:905227*90522793037825152Streptococcus parauberis KCTC 11537 chromosome, complete genome5e-0661.9BLASTN svgBLASTP svg
NC_012440:197728*19772822123323506Persephonella marina EX-H1, complete genome5e-0661.9BLASTN svgBLASTP svg
NC_009782:1327340*1327340135080023461Staphylococcus aureus subsp. aureus Mu3, complete genome5e-0661.9BLASTN svgBLASTP svg
NC_005957:3638750*3638750365855919810Bacillus thuringiensis serovar konkukian str. 97-27, complete5e-0661.9BLASTN svgBLASTP svg