Pre_GI: BLASTN Hits

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Query: NC_012563:811993 Clostridium botulinum A2 str. Kyoto, complete genome

Start: 811993, End: 830647, Length: 18655

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:20640272064027208498120955Clostridium botulinum B1 str. Okra, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_010516:3845942*3845942386860822667Clostridium botulinum B1 str. Okra, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010516:27772052777205280241925215Clostridium botulinum B1 str. Okra, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_010520:3204480*3204480322378019301Clostridium botulinum A3 str. Loch Maree, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_012563:2230403*2230403225235521953Clostridium botulinum A2 str. Kyoto, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_012563:3580000*3580000360253222533Clostridium botulinum A2 str. Kyoto, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_021182:37715233771523379409922577Clostridium pasteurianum BC1, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_006814:403723*40372344563241910Lactobacillus acidophilus NCFM, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_010516:3234791*3234791325832823538Clostridium botulinum B1 str. Okra, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_010516:3196158*3196158321545819301Clostridium botulinum B1 str. Okra, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_012563:32881243288124330917721054Clostridium botulinum A2 str. Kyoto, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_021182:11880001188000121083922840Clostridium pasteurianum BC1, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_010520:15860001586000160832222323Clostridium botulinum A3 str. Loch Maree, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_012563:29791472979147300249023344Clostridium botulinum A2 str. Kyoto, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_010520:31205003120500313949618997Clostridium botulinum A3 str. Loch Maree, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_010516:34660003466000348809922100Clostridium botulinum B1 str. Okra, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_021182:20135002013500203160018101Clostridium pasteurianum BC1, complete genome9e-0660BLASTN svgBLASTP svg
NC_010520:28074292807429283431926891Clostridium botulinum A3 str. Loch Maree, complete genome9e-0660BLASTN svgBLASTP svg
NC_010520:21715842171584219449022907Clostridium botulinum A3 str. Loch Maree, complete genome9e-0660BLASTN svgBLASTP svg