Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS




NC_017297: Clostridium botulinum F str. 230613 chromosome, complete genome

NCBI: NC_017297

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
11*1925819258Island text6.7405721.627141.419Neighbours21BLASTN1.gbk
233519*7959946081Island text5.9234122.871242.8743Neighbours344BLASTN+33519.gbk
3122383*14531422932Island text4.8063620.322633.5524Neighbours21BLASTN122383.gbk
4490922*51709926178Island text4.4934623.355442.5256Neighbours21BLASTN+490922.gbk
556472758403319307Island text3.7942418.360923.6356Neighbours21BLASTN564727.gbk
61280963130030419342Island text2.9495418.579826.1908Neighbours21BLASTN+1280963.gbk
71352506*137491822413Island text4.3649619.737435.1707Neighbours21BLASTN+1352506.gbk
81402349142209919751Island text2.9333517.975935.0648Neighbours21BLASTN1402349.gbk
91700000172353723538Island text2.525617.798534.8337Neighbours21BLASTN+1700000.gbk
102017000203782620827Island text3.9081418.570438.624Neighbours21BLASTN+2017000.gbk
112054000207616222163Island text2.8042818.084430.9416Neighbours21BLASTN+2054000.gbk
122114222213459920378Island text2.547618.462233.107Neighbours21BLASTN+2114222.gbk
132143000*216395220953Island text2.0300220.046726.8283Neighbours21BLASTN+2143000.gbk
142288000231122723228Island text2.440418.306231.4716Neighbours21BLASTN2288000.gbk
152531750*257137439625Island text3.2590518.296634.4465Neighbours21BLASTN+2531750.gbk
162575306*259359918294Island text2.8031818.476435.1504Neighbours21BLASTN2575306.gbk
172635892*267643140540Island text2.9808618.212233.34Neighbours21BLASTN+2635892.gbk
182796000281809922100Island text1.8654317.002126.3613Neighbours323BLASTN+2796000.gbk
192854934286937214439Island text3.0253117.801132.1353Neighbours21BLASTN2854934.gbk
202905138292809922962Island text3.4257418.170836.6887Neighbours21BLASTN2905138.gbk
213178378*320035721980Island text3.5592319.142835.3108Neighbours21BLASTN3178378.gbk
223428429345459926171Island text3.9918720.650738.9187Neighbours21BLASTN+3428429.gbk
233546467*356461318147Island text2.0115618.385235.522Neighbours21BLASTN+3546467.gbk
243594000361677222773Island text2.3983518.257530.1377Neighbours21BLASTN+3594000.gbk
253752000377386721868Island text3.0714118.235432.9898Neighbours21BLASTN+3752000.gbk
263787191*381771830528Island text3.5374318.950136.1838Neighbours21BLASTN+3787191.gbk
273838189*387075832570Island text4.5098521.613840.3856Neighbours21BLASTN3838189.gbk
283878540*389687818339Island text3.3500618.415633.0125Neighbours21BLASTN3878540.gbk
293939328*397827538948Island text2.716819.176434.7788Neighbours21BLASTN3939328.gbk