Pre_GI Gene

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Host: NC_017297 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017297:3787191 Clostridium botulinum F str. 230613 chromosome, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
378719137888071617NaPi-cotransporter family proteinPhoU family proteinQuickGO ontologyBLASTP
3789113378950539330S ribosomal protein S9QuickGO ontologyBLASTP
3789531378996843850S ribosomal protein L13QuickGO ontologyBLASTP
37900893790829741tRNA pseudouridine synthase AQuickGO ontologyBLASTP
37908293791632804cobalt transport permease CbiQ familyQuickGO ontologyBLASTP
37916293792495867putative cobalt ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
37924803793328849putative cobalt ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
3793419379376034250S ribosomal protein L17QuickGO ontologyBLASTP
37938043794751948DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
3794819379543962130S ribosomal protein S4QuickGO ontologyBLASTP
3795474379587239930S ribosomal protein S11QuickGO ontologyBLASTP
3795890379626137230S ribosomal protein S13QuickGO ontologyBLASTP
3796374379648711450S ribosomal protein L2QuickGO ontologyBLASTP
37965043796722219translation initiation factor IF-1QuickGO ontologyBLASTP
37967303797011282hypothetical proteinBLASTP
37970263797775750methionine aminopeptidaseQuickGO ontologyBLASTP
37977753798425651adenylate kinaseQuickGO ontologyBLASTP
379844937997261278preprotein translocase subunit SecYQuickGO ontologyBLASTP
3799727380016744150S ribosomal protein L15QuickGO ontologyBLASTP
3800187380036618050S ribosomal protein L30QuickGO ontologyBLASTP
3800380380087749830S ribosomal protein S5QuickGO ontologyBLASTP
3800895380125436050S ribosomal protein L18QuickGO ontologyBLASTP
3801273380181554350S ribosomal protein L6QuickGO ontologyBLASTP
3801839380223739930S ribosomal protein S8QuickGO ontologyBLASTP
3802267380245218630S ribosomal protein S14QuickGO ontologyBLASTP
3802469380301154350S ribosomal protein L5QuickGO ontologyBLASTP
3803034380335131850S ribosomal protein L24QuickGO ontologyBLASTP
3803375380374336950S ribosomal protein L14QuickGO ontologyBLASTP
3803778380403225530S ribosomal protein S17QuickGO ontologyBLASTP
3804054380426621350S ribosomal protein L29QuickGO ontologyBLASTP
3804256380469944450S ribosomal protein L16QuickGO ontologyBLASTP
3804717380538867230S ribosomal protein S3QuickGO ontologyBLASTP
3805406380574133650S ribosomal protein L22QuickGO ontologyBLASTP
3805763380604728530S ribosomal protein S19QuickGO ontologyBLASTP
3806117380695083450S ribosomal protein L2QuickGO ontologyBLASTP
3807005380729829450S ribosomal protein L23QuickGO ontologyBLASTP
3807298380791862150S ribosomal protein L4QuickGO ontologyBLASTP
3807943380857263050S ribosomal protein L3QuickGO ontologyBLASTP
3808662380897030930S ribosomal protein S10QuickGO ontologyBLASTP
381059338126622070translation elongation factor GQuickGO ontologyBLASTP
3812734381320447130S ribosomal protein S7QuickGO ontologyBLASTP
3813365381374237830S ribosomal protein S12QuickGO ontologyBLASTP
38138183814060243ribosomal protein L7Ae family proteinQuickGO ontologyBLASTP
381418238177183537DNA-directed RNA polymerase subunit betaQuickGO ontologyBLASTP