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Query: NC_017297:2054000 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 2054000, End: 2076162, Length: 22163

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:19995001999500201784518346Clostridium botulinum B1 str. Okra, complete genome05364BLASTN svgBLASTP svg
NC_010520:20615022061502208422422723Clostridium botulinum A3 str. Loch Maree, complete genome04540BLASTN svgBLASTP svg
NC_012563:21014492101449212008818640Clostridium botulinum A2 str. Kyoto, complete genome2e-34155BLASTN svgBLASTP svg
NC_010520:16143331614333164965435322Clostridium botulinum A3 str. Loch Maree, complete genome8e-25123BLASTN svgBLASTP svg
NC_014377:1227850*1227850127023442385Thermosediminibacter oceani DSM 16646 chromosome, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014833:3444550*3444550347132026771Ruminococcus albus 7 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_011661:10497671049767106859918833Dictyoglomus turgidum DSM 6724, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_010723:10143341014334103372419391Clostridium botulinum E3 str. Alaska E43, complete genome3e-0661.9BLASTN svgBLASTP svg