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Query: NC_017297:3878540 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 3878540, End: 3896878, Length: 18339

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:3845942*3845942386860822667Clostridium botulinum B1 str. Okra, complete genome04548BLASTN svgBLASTP svg
NC_020291:117983*11798315068032698Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-33151BLASTN svgBLASTP svg
NC_008262:2649289*2649289270467655388Clostridium perfringens SM101, complete genome1e-20109BLASTN svgBLASTP svg
NC_009922:2850320*2850320287198821669Alkaliphilus oremlandii OhILAs, complete genome4e-20107BLASTN svgBLASTP svg
NC_014614:554949*55494957879923851Clostridium sticklandii, complete genome6e-19103BLASTN svgBLASTP svg
NC_019978:91483*9148311073919257Halobacteroides halobius DSM 5150, complete genome4e-1797.6BLASTN svgBLASTP svg
NS_000191:1037899*1037899106009922201Uncultured Termite group 1 bacterium phylotype Rs-D17, complete2e-1281.8BLASTN svgBLASTP svg
NC_011899:2286884*2286884231116224279Halothermothrix orenii H 168, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_014393:19016881901688192179720110Clostridium cellulovorans 743B chromosome, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_009718:643200*64320068474241543Fervidobacterium nodosum Rt17-B1, complete genome2e-0661.9BLASTN svgBLASTP svg