Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS




NC_007530: Bacillus anthracis str. 'Ames Ancestor', complete genome

NCBI: NC_007530

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
146799349066022668Island text1.5523520.710737.0325Neighbours21BLASTN+IslandViewer 467993.gbk
267426569315018886Island text1.6106122.574226.6415Neighbours21BLASTN+674265.gbk
31007140*102671019571Island text1.5283822.686631.77Neighbours21BLASTN+1007140.gbk
41068000109028722288Island text2.5040622.753538.6222Neighbours21BLASTN1068000.gbk
51332768135609923332Island text1.8286922.653240.4861Neighbours21BLASTN1332768.gbk
61459412148366224251Island text1.5640420.102735.7108Neighbours21BLASTN1459412.gbk
71523060154955226493Island text1.5577322.686630.2656Neighbours21BLASTN+1523060.gbk
82175967219810122135Island text1.6260720.975234.7545Neighbours21BLASTN+2175967.gbk
92716885273695220068Island text1.53922.419130.497Neighbours21BLASTN2716885.gbk
103321033334647025438Island text1.617920.476734.2673Neighbours21BLASTN+3321033.gbk
113414568344282128254Island text1.6738926.866935.4981Neighbours21BLASTN+3414568.gbk
123462624348669024067Island text1.6464722.10335.4002Neighbours21BLASTN+IslandViewer 3462624.gbk
133581202360051619315Island text1.6729322.315835.7961NeighboursBLASTN3581202.gbk
143616828*367637859551Island text1.7434522.995934.2089Neighbours21BLASTN3616828.gbk
153694940*372015325214Island text1.6760325.510736.9533Neighbours21BLASTN3694940.gbk
163724829*374846023632Island text1.862222.71137.3371Neighbours21BLASTN+3724829.gbk
173749645376944819804Island text2.2314122.124337.5137Neighbours21BLASTN+IslandViewer 3749645.gbk
183992228401145819231Island text1.6087623.449732.9719Neighbours21BLASTN3992228.gbk
194117071*413809921029Island text1.5912823.369934.7476Neighbours21BLASTN4117071.gbk
204176462*420041823957Island text1.7286722.595535.5342Neighbours21BLASTN4176462.gbk
214251773*427368821916Island text1.6923323.220532.187Neighbours21BLASTN4251773.gbk
224400152441849918348Island text1.609422.972433.9932Neighbours21BLASTN4400152.gbk
234474000*449681122812Island text1.8435322.820440.2668Neighbours21BLASTN4474000.gbk
244507742452659918858Island text1.6276723.597139.609Neighbours21BLASTN4507742.gbk
254674335469287518541Island text1.6132223.078833.2836NeighboursBLASTN4674335.gbk
264744870476579920930Island text1.5292123.768331.8282Neighbours21BLASTN4744870.gbk
274853740*487494821209Island text1.5666326.136933.6815Neighbours21BLASTN+IslandViewer 4853740.gbk
284877500*491960442105Island text1.6980223.841936.7995Neighbours21BLASTN+4877500.gbk
295006319503097224654Island text1.6382722.597135.8022Neighbours21BLASTN+5006319.gbk
305033095*507221139117Island text1.6510923.891235.9716Neighbours21BLASTN5033095.gbk
315197854*521982221969Island text1.6107121.221431.7274Neighbours21BLASTN5197854.gbk