Pre_GI: BLASTN Hits

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Query: NC_007530:3992228 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 3992228, End: 4011458, Length: 19231

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_005945:39926003992600401183019231Bacillus anthracis str. Sterne, complete genome022790BLASTN svgBLASTP svg
NC_003997:39932233993223401133118109Bacillus anthracis str. Ames, complete genome022790BLASTN svgBLASTP svg
NC_008600:39760453976045399505219008Bacillus thuringiensis str. Al Hakam, complete genome022560BLASTN svgBLASTP svg
NC_014335:39021553902155392084118687Bacillus cereus biovar anthracis str. CI chromosome, complete022090BLASTN svgBLASTP svg
NC_006274:40312464031246404927818033Bacillus cereus E33L, complete genome021820BLASTN svgBLASTP svg
NC_005957:39751923975192399978024589Bacillus thuringiensis serovar konkukian str. 97-27, complete021560BLASTN svgBLASTP svg
NC_003909:39412823941282396026818987Bacillus cereus ATCC 10987, complete genome018680BLASTN svgBLASTP svg
NC_004722:41174594117459413677919321Bacillus cereus ATCC 14579, complete genome015790BLASTN svgBLASTP svg
NC_011772:41259964125996414521919224Bacillus cereus G9842, complete genome015770BLASTN svgBLASTP svg
NC_010184:40216884021688404437322686Bacillus weihenstephanensis KBAB4, complete genome014990BLASTN svgBLASTP svg
NC_012793:23377762337776236019822423Geobacillus sp. WCH70, complete genome9e-83315BLASTN svgBLASTP svg
NC_016047:24809212480921250892228002Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, complete2e-1385.7BLASTN svgBLASTP svg
NC_003869:20990002099000211791718918Thermoanaerobacter tengcongensis MB4, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_014976:3469395*3469395348959920205Bacillus subtilis BSn5 chromosome, complete genome9e-0660BLASTN svgBLASTP svg