Pre_GI Gene

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Host: NC_007530 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007530:5033095 Bacillus anthracis str. 'Ames Ancestor', complete genome

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
503309550358242730sensory boxggdef family proteinQuickGO ontologyBLASTP
50358965036549654hypothetical proteinBLASTP
50365975037388792hypothetical proteinBLASTP
50375105037911402ATP synthase subunit epsilonQuickGO ontologyBLASTP
503793250393411410ATP synthase subunit BQuickGO ontologyBLASTP
50394615040321861ATP synthase subunit CQuickGO ontologyBLASTP
504065750421651509ATP synthase subunit AQuickGO ontologyBLASTP
50421775042719543ATP synthase subunit DQuickGO ontologyBLASTP
50427165043222507ATP synthase subunit BQuickGO ontologyBLASTP
50433505043568219ATP synthase subunit CQuickGO ontologyBLASTP
50436255044344720ATP synthase subunit AQuickGO ontologyBLASTP
50443525044744393atp synthase protein iQuickGO ontologyBLASTP
50447445044998255hypothetical proteinBLASTP
50449955045108114hypothetical proteinBLASTP
50454805046109630uracil phosphoribosyltransferaseQuickGO ontologyBLASTP
504638150476221242serine hydroxymethyltransferaseQuickGO ontologyBLASTP
50478395048411573conserved hypothetical protein tigr01440QuickGO ontologyBLASTP
50484785048921444ribose-5-phosphate isomerase BQuickGO ontologyBLASTP
50490185049458441low molecular weight phosphotyrosine protein phosphatase family proteinQuickGO ontologyBLASTP
50497065050203498pts system glucose-specific iia component putativeQuickGO ontologyBLASTP
50505905050976387hypothetical proteinBLASTP
50511365051747612hypothetical proteinBLASTP
50519405052284345hypothetical proteinBLASTP
50524495052997549hypothetical proteinBLASTP
505307550541151041sua5ycioyrdcywlc family proteinQuickGO ontologyBLASTP
50542245054682459hypothetical proteinBLASTP
50547325055598867stage ii sporulation protein r putativeQuickGO ontologyBLASTP
50557115056562852modification methylase hemk familyQuickGO ontologyBLASTP
505656250576291068peptide chain release factor 1QuickGO ontologyBLASTP
50579005058484585thymidine kinaseQuickGO ontologyBLASTP
5058593505883824650S ribosomal protein L31QuickGO ontologyBLASTP
505924250605131272transcription termination factor RhoQuickGO ontologyBLASTP
50608565061821966fructose-16-bisphosphatase class iiQuickGO ontologyBLASTP
50618375061938102hypothetical proteinBLASTP
506193950632281290UDP-N-acetylglucosamine 1-carboxyvinyltransferaseQuickGO ontologyBLASTP
50635605064417858fructose-bisphosphate aldolaseQuickGO ontologyBLASTP
50646285064996369stage 0 sporulation protein fQuickGO ontologyBLASTP
50651985065722525hypothetical proteinBLASTP
506575450673611608CTP synthetaseQuickGO ontologyBLASTP
50676195068146528DNA-directed RNA polymerase delta subunitQuickGO ontologyBLASTP
50683015068903603transcriptional regulator tetr familyQuickGO ontologyBLASTP
506899550701341140acyl-coa dehydrogenaseQuickGO ontologyBLASTP
507015650712861131acyl-coa dehydrogenaseQuickGO ontologyBLASTP
507136050722118523-hydroxybutyryl-CoA dehydrogenaseQuickGO ontologyBLASTP