Query: NC_007530:4507742 Bacillus anthracis str. 'Ames Ancestor', complete genome
Start: 4507742, End: 4526599, Length: 18858
Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_003997:4507939 | 4507939 | 4526687 | 18749 | Bacillus anthracis str. Ames, complete genome | 0 | 30330 | BLASTN svg | BLASTP svg |
NC_005945:4508304* | 4508304 | 4532099 | 23796 | Bacillus anthracis str. Sterne, complete genome | 0 | 17570 | BLASTN svg | BLASTP svg |
NC_006274:4563455* | 4563455 | 4587393 | 23939 | Bacillus cereus E33L, complete genome | 0 | 14820 | BLASTN svg | BLASTP svg |
NC_012472:4515909* | 4515909 | 4541710 | 25802 | Bacillus cereus 03BB102, complete genome | 0 | 14720 | BLASTN svg | BLASTP svg |
NC_008600:4509793* | 4509793 | 4535599 | 25807 | Bacillus thuringiensis str. Al Hakam, complete genome | 0 | 14720 | BLASTN svg | BLASTP svg |
NC_005957:4502733* | 4502733 | 4529411 | 26679 | Bacillus thuringiensis serovar konkukian str. 97-27, complete | 0 | 14440 | BLASTN svg | BLASTP svg |
NC_003909:4484278* | 4484278 | 4511799 | 27522 | Bacillus cereus ATCC 10987, complete genome | 0 | 11740 | BLASTN svg | BLASTP svg |
NC_004722:4645678 | 4645678 | 4669217 | 23540 | Bacillus cereus ATCC 14579, complete genome | 0 | 9688 | BLASTN svg | BLASTP svg |
NC_014335:4442500 | 4442500 | 4460472 | 17973 | Bacillus cereus biovar anthracis str. CI chromosome, complete | 0 | 9616 | BLASTN svg | BLASTP svg |
NC_010184:4532262* | 4532262 | 4558887 | 26626 | Bacillus weihenstephanensis KBAB4, complete genome | 0 | 7810 | BLASTN svg | BLASTP svg |
NC_011772:4638000* | 4638000 | 4661925 | 23926 | Bacillus cereus G9842, complete genome | 0 | 7125 | BLASTN svg | BLASTP svg |
NC_020244:516993* | 516993 | 551153 | 34161 | Bacillus subtilis XF-1, complete genome | 1e-17 | 99.6 | BLASTN svg | BLASTP svg |
NC_014976:2735423* | 2735423 | 2761367 | 25945 | Bacillus subtilis BSn5 chromosome, complete genome | 1e-17 | 99.6 | BLASTN svg | BLASTP svg |
NC_000964:521975* | 521975 | 561933 | 39959 | Bacillus subtilis subsp. subtilis str. 168, complete genome | 2e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_019896:3491000* | 3491000 | 3524735 | 33736 | Bacillus subtilis subsp. subtilis str. BSP1 chromosome, complete | 2e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_005945:754517 | 754517 | 773745 | 19229 | Bacillus anthracis str. Sterne, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_014479:509919* | 509919 | 539862 | 29944 | Bacillus subtilis subsp. spizizenii str. W23 chromosome, complete | 6e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_005957:4311679 | 4311679 | 4334500 | 22822 | Bacillus thuringiensis serovar konkukian str. 97-27, complete | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_019842:484933* | 484933 | 542778 | 57846 | Bacillus amyloliquefaciens subsp. plantarum AS43.3 chromosome, | 2e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_020410:495184* | 495184 | 541626 | 46443 | Bacillus amyloliquefaciens subsp. plantarum UCMB5036 complete | 2e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_009725:496443* | 496443 | 549912 | 53470 | Bacillus amyloliquefaciens FZB42, complete genome | 2e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_013406:5954472 | 5954472 | 5978397 | 23926 | Paenibacillus sp. Y412MC10 chromosome, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
CP002207:1 | 1 | 34666 | 34666 | Bacillus atrophaeus 1942, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
UCMB5137:1* | 1 | 38370 | 38370 | Bacillus atrophaeus UCMB-5137 | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_006582:883922* | 883922 | 914599 | 30678 | Bacillus clausii KSM-K16, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_007530:3321033 | 3321033 | 3346470 | 25438 | Bacillus anthracis str. 'Ames Ancestor', complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_005945:3321600 | 3321600 | 3344771 | 23172 | Bacillus anthracis str. Sterne, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_003997:3320906 | 3320906 | 3346343 | 25438 | Bacillus anthracis str. Ames, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |