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Query: NC_007530:4176462 Bacillus anthracis str. 'Ames Ancestor', complete genome

Start: 4176462, End: 4200418, Length: 23957

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This is the type strain (0581, A2084, genotype 62, Group A3.b) for Bacillus anthracis and contains the two virulence plasmids, pOX1 and pOX2, that encode anthrax toxin and capsule, respectively, making this a virulent strain. This strain is considered the "gold standard" for B. anthracis. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_005957:4169610*4169610419274423135Bacillus thuringiensis serovar konkukian str. 97-27, complete031400BLASTN svgBLASTP svg
NC_014335:4113154*4113154413214818995Bacillus cereus biovar anthracis str. CI chromosome, complete031250BLASTN svgBLASTP svg
NC_011772:4321117*4321117433922618110Bacillus cereus G9842, complete genome015490BLASTN svgBLASTP svg
NC_010184:4219257*4219257423766018404Bacillus weihenstephanensis KBAB4, complete genome08264BLASTN svgBLASTP svg
NC_015391:695350*69535071865123302Carnobacterium sp. 17-4 chromosome, complete genome9e-28133BLASTN svgBLASTP svg
NC_020272:1311932*1311932135853446603Bacillus amyloliquefaciens IT-45, complete genome1e-23119BLASTN svgBLASTP svg
NC_011025:183287*18328722741244126Mycoplasma arthritidis 158L3-1, complete genome8e-1383.8BLASTN svgBLASTP svg
NC_004368:53307533077491321607Streptococcus agalactiae NEM316, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_018515:989616*989616101215322538Desulfosporosinus meridiei DSM 13257 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_007296:35661356616061124951Streptococcus pyogenes MGAS6180, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_007930:18028118028119859918319Lactobacillus salivarius subsp. salivarius UCC118 plasmid pMP118,5e-0867.9BLASTN svgBLASTP svg
NC_014166:401815*40181542611724303Arcobacter nitrofigilis DSM 7299 chromosome, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_011134:51218*512187644125224Streptococcus equi subsp. zooepidemicus str. MGCS10565, complete7e-0763.9BLASTN svgBLASTP svg
NC_004557:2289135*2289135231328724153Clostridium tetani E88, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_003366:2057656*2057656208209924444Clostridium perfringens str. 13, complete genome3e-0661.9BLASTN svgBLASTP svg