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Query: NC_009699:564455 Clostridium botulinum F str. Langeland chromosome, complete genome

Start: 564455, End: 584788, Length: 20334

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum F strain Langeland was identified in 1958 from home-prepared liver paste involved in an outbreak of foodborne botulism on the island of Langeland, in Denmark. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:583870*58387060159917730Clostridium botulinum B1 str. Okra, complete genome03747BLASTN svgBLASTP svg
NC_010520:28074292807429283431926891Clostridium botulinum A3 str. Loch Maree, complete genome2e-19105BLASTN svgBLASTP svg
NC_010516:3196158*3196158321545819301Clostridium botulinum B1 str. Okra, complete genome4e-1797.6BLASTN svgBLASTP svg
NC_012563:2230403*2230403225235521953Clostridium botulinum A2 str. Kyoto, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_010516:3903867*3903867395059846732Clostridium botulinum B1 str. Okra, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_008593:37456*374566080623351Clostridium novyi NT, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_008593:2457594*2457594250471047117Clostridium novyi NT, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_004557:2078000*2078000210049622497Clostridium tetani E88, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_003366:72885972885975493526077Clostridium perfringens str. 13, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_008261:676000*67600070224526246Clostridium perfringens ATCC 13124, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_008262:654000*65400067859924600Clostridium perfringens SM101, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_012563:4101000*4101000412265321654Clostridium botulinum A2 str. Kyoto, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_010520:3938490*3938490397609937610Clostridium botulinum A3 str. Loch Maree, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_010520:3204480*3204480322378019301Clostridium botulinum A3 str. Loch Maree, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_010520:11460001146000116884922850Clostridium botulinum A3 str. Loch Maree, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_010520:72531272531274947124160Clostridium botulinum A3 str. Loch Maree, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_012778:403962*40396242480720846Eubacterium eligens ATCC 27750, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_012778:2015409*2015409203979424386Eubacterium eligens ATCC 27750, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_003366:25548025548029721641737Clostridium perfringens str. 13, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_004557:691944*69194471563123688Clostridium tetani E88, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_008261:225425*22542525641730993Clostridium perfringens ATCC 13124, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_008262:227354*22735427081243459Clostridium perfringens SM101, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_010516:3845942*3845942386860822667Clostridium botulinum B1 str. Okra, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_012563:24660002466000248852922530Clostridium botulinum A2 str. Kyoto, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_009089:370555*37055539409923545Clostridium difficile 630, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_012563:32881243288124330917721054Clostridium botulinum A2 str. Kyoto, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_013316:371953*37195339532823376Clostridium difficile R20291, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_010723:37174137174139352221782Clostridium botulinum E3 str. Alaska E43, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_010516:23740002374000239681422815Clostridium botulinum B1 str. Okra, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_021182:93000*9300014465551656Clostridium pasteurianum BC1, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014393:92500*9250013027937780Clostridium cellulovorans 743B chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_010674:37062937062939810727479Clostridium botulinum B str. Eklund 17B, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_015687:3766000*3766000379114625147Clostridium acetobutylicum DSM 1731 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_003030:3763054*3763054378965126598Clostridium acetobutylicum ATCC 824, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_009922:2590317*2590317261009919783Alkaliphilus oremlandii OhILAs, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_011898:2907017*2907017292585518839Clostridium cellulolyticum H10, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_014387:1175927*1175927120709031164Butyrivibrio proteoclasticus B316 chromosome 1, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_021182:37715233771523379409922577Clostridium pasteurianum BC1, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_014614:554949*55494957879923851Clostridium sticklandii, complete genome9e-0660BLASTN svgBLASTP svg
NC_014614:2500301*2500301252659926299Clostridium sticklandii, complete genome9e-0660BLASTN svgBLASTP svg
NC_014410:25117532511753253648824736Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,9e-0660BLASTN svgBLASTP svg
NC_009922:1917271*1917271193756720297Alkaliphilus oremlandii OhILAs, complete genome9e-0660BLASTN svgBLASTP svg