Pre_GI Gene

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Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:3196158 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
31961583196856699diacylglycerol kinasePAP2 family proteinQuickGO ontologyBLASTP
31968973197397501conserved hypothetical protein TIGR00043QuickGO ontologyBLASTP
319739431994812088putative hydrolaseQuickGO ontologyBLASTP
319950432006641161putative stage IV sporulation proteinQuickGO ontologyBLASTP
32006543200950297sporulation protein YqfCQuickGO ontologyBLASTP
32010643201510447GatBYqey domain proteinQuickGO ontologyBLASTP
32015533201729177ribosomal protein S21QuickGO ontologyBLASTP
32018663202210345HIT family proteinQuickGO ontologyBLASTP
320226732035651299RNA modification enzyme MiaB familyQuickGO ontologyBLASTP
32035653204323759conserved hypothetical protein TIGR00046QuickGO ontologyBLASTP
32044213205359939ribosomal protein L11 methyltransferaseQuickGO ontologyBLASTP
320566732068121146chaperone protein DnaJQuickGO ontologyBLASTP
320695532088261872chaperone protein DnaKQuickGO ontologyBLASTP
32088813209525645co-chaperone GrpEQuickGO ontologyBLASTP
320955232105831032heat-inducible transcriptional repressor HrcAQuickGO ontologyBLASTP
321078432119261143putative oxygen-independent coproporphyrinogen III oxidaseQuickGO ontologyBLASTP
321195332137611809GTP-binding protein LepAQuickGO ontologyBLASTP
32139023214297396hypothetical proteinBLASTP
321436732154581092stage II sporulation proteinQuickGO ontologyBLASTP