Pre_GI: BLASTP Hits

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Query: NC_010516:3196158:3214367 Clostridium botulinum B1 str. Okra, complete genome

Start: 3214367, End: 3215458, Length: 1092

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:3178378:3197068319706831981591092Clostridium botulinum F str. 230613 chromosome, complete genomestage II sporulation protein1e-179629
NC_009699:3178222:3196913319691331980041092Clostridium botulinum F str. Langeland chromosome, complete genomestage II sporulation protein1e-179629
NC_012563:3374904:3392982339298233940731092Clostridium botulinum A2 str. Kyoto, complete genomestage II sporulation protein2e-179628
NC_009697:3071198:3089276308927630903671092Clostridium botulinum A str. ATCC 19397 chromosome, completestage II sporulation protein8e-179626
NC_009495:3138355:3156433315643331575241092Clostridium botulinum A str. ATCC 3502 chromosome, complete genomestage II sporulation protein8e-179626
NC_010520:3204480:3222689322268932237801092Clostridium botulinum A3 str. Loch Maree, complete genomestage II sporulation protein4e-176617
NC_021182:2192718:2197653219765321987621110Clostridium pasteurianum BC1, complete genomestage II sporulation protein P9e-70264
NC_021182:2667408:2671982267198226730821101Clostridium pasteurianum BC1, complete genomestage II sporulation protein P9e-66250
NC_008593:1704207:1720823172082317219291107Clostridium novyi NT, complete genomestage II sporulation protein P1e-46187
NC_015519:1113095:1136604113660411378781275Tepidanaerobacter sp. Re1 chromosome, complete genomestage II sporulation protein P5e-25115
NC_009012:1595498:1611804161180416130811278Clostridium thermocellum ATCC 27405, complete genomeStage II sporulation P1e-22107
NC_016627:3205333:3225854322585432270981245Clostridium clariflavum DSM 19732 chromosome, complete genomestage II sporulation protein P8e-22104
NC_009633:3055413:3087765308776530890181254Alkaliphilus metalliredigens QYMF chromosome, complete genomestage II sporulation P family protein2e-1996.7
NC_014831:388007:411240411240412118879Thermaerobacter marianensis DSM 12885 chromosome, complete genomestage II sporulation protein P3e-1789.7
NC_014377:961259:9634479634479646161170Thermosediminibacter oceani DSM 16646 chromosome, complete genomestage II sporulation protein P2e-1480.5
NC_015519:1205049:1205049120504912062151167Tepidanaerobacter sp. Re1 chromosome, complete genomestage II sporulation protein P2e-1377
NC_007644:1352794:1370971137097113722631293Moorella thermoacetica ATCC 39073, complete genomestage II sporulation protein P4e-1272.4
NC_013216:3408608:342911834291183430068951Desulfotomaculum acetoxidans DSM 771, complete genomestage II sporulation protein P3e-1169.7
NC_015589:2999735:2999735299973530010151281Desulfotomaculum ruminis DSM 2154 chromosome, complete genomestage II sporulation protein P4e-0962.4
NC_010001:2836995:2855781285578128572321452Clostridium phytofermentans ISDg, complete genomeStage II sporulation P family protein2e-0860.5