Pre_GI: BLASTP Hits

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Query: NC_010516:3196158:3197394 Clostridium botulinum B1 str. Okra, complete genome

Start: 3197394, End: 3199481, Length: 2088

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009495:3138355:3139589313958931416762088Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehydrolase01285
NC_017297:3178378:3180096318009631821832088Clostridium botulinum F str. 230613 chromosome, complete genomeputative hydrolase01284
NC_009699:3178222:3179940317994031820272088Clostridium botulinum F str. Langeland chromosome, complete genomehydrolase01284
NC_009698:3006500:3009354300935430114412088Clostridium botulinum A str. Hall chromosome, complete genomehydrolase01284
NC_009697:3071198:3072432307243230745192088Clostridium botulinum A str. ATCC 19397 chromosome, completehydrolase01284
NC_012563:3374904:3376140337614033782272088Clostridium botulinum A2 str. Kyoto, complete genomeputative hydrolase01283
NC_010520:3204480:3205716320571632078032088Clostridium botulinum A3 str. Loch Maree, complete genomeputative hydrolase01283
NC_012658:3213498:3214734321473432168212088Clostridium botulinum Ba4 str. 657 chromosome, complete genomeputative hydrolase01281
NC_008593:1704207:1704207170420717062342028Clostridium novyi NT, complete genomeMembrane protein containing HD superfamily hydrolase domain0761
NC_021182:2192718:2214409221440922164632055Clostridium pasteurianum BC1, complete genomeputative domain HDIG-containing protein0730
NC_008261:2524913:2524913252491325269672055Clostridium perfringens ATCC 13124, complete genomeputative hydrolase1e-172607
NC_020291:1014333:1030729103072910328162088Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomemetal dependent phosphohydrolase2e-164580
NC_009633:3055413:3063099306309930653092211Alkaliphilus metalliredigens QYMF chromosome, complete genomemetal dependent phosphohydrolase3e-118426
NC_011898:649000:6669726669726692092238Clostridium cellulolyticum H10, complete genomemetal dependent phosphohydrolase2e-101370
NC_002570:1426000:1447441144744114496062166Bacillus halodurans C-125, complete genomehypothetical protein4e-98359
NC_018515:4148037:4148729414872941509962268Desulfosporosinus meridiei DSM 13257 chromosome, complete genomehypothetical protein2e-91337
NC_009674:3073564:3075693307569330778372145Bacillus cytotoxicus NVH 391-98 chromosome, complete genomemetal dependent phosphohydrolase2e-87323
NC_016771:4059445:4063498406349840656422145Bacillus cereus NC7401, complete genomeHDIG domain-containing protein1e-85318
NC_011969:4001489:4004802400480240069462145Bacillus cereus Q1 chromosome, complete genomemetal-dependent phosphohydrolase1e-85318
NC_011658:4107501:4109714410971441118582145Bacillus cereus AH187 chromosome, complete genomeHDIG domain-containing protein1e-85318
NC_005957:4104880:4104880410488041070242145Bacillus thuringiensis serovar konkukian str. 97-27, completemetal-dependent phosphohydrolase4e-84313
NC_005945:4116978:4117445411744541195892145Bacillus anthracis str. Sterne, complete genomeHDIG domain protein5e-84312
NC_012472:4119192:4121405412140541235492145Bacillus cereus 03BB102, complete genomeHDIG domain protein5e-84312
NC_007530:4117071:4117071411707141192152145Bacillus anthracis str. 'Ames Ancestor', complete genomehdig domain protein5e-84312
NC_008600:4101748:4103961410396141061052145Bacillus thuringiensis str. Al Hakam, complete genomemetal-dependent phosphohydrolase5e-84312
NC_003997:4116944:4116944411694441190882145Bacillus anthracis str. Ames, complete genomeHDIG domain protein5e-84312
NC_006274:4159096:4159096415909641612402145Bacillus cereus E33L, complete genomemetal-dependent phosphohydrolase5e-84312
NC_011773:4108855:4108855410885541109992145Bacillus cereus AH820 chromosome, complete genomeHDIG domain protein5e-84312
NC_012581:4118366:4118366411836641205102145Bacillus anthracis str. CDC 684 chromosome, complete genomeHDIG domain protein5e-84312
NC_012659:4116971:4116971411697141191152145Bacillus anthracis str. A0248, complete genomeHDIG domain protein5e-84312
NC_016779:4039103:4039103403910340412472145Bacillus cereus F837/76 chromosome, complete genomeMembrane protein5e-84312
NC_014335:4027105:4027105402710540292492145Bacillus cereus biovar anthracis str. CI chromosome, completemetal dependent phosphohydrolase5e-84312
NC_003909:4064904:4065371406537140675152145Bacillus cereus ATCC 10987, complete genomeHDIG domain protein5e-81302
NC_010184:4155345:4155345415534541574892145Bacillus weihenstephanensis KBAB4, complete genomemetal dependent phosphohydrolase2e-80301
NC_013517:2055071:2072231207223120743212091Sebaldella termitidis ATCC 33386, complete genome7TM receptor with intracellular metal dependent phosphohydrolase4e-80299
NC_007759:1571425:1591481159148115938292349Syntrophus aciditrophicus SB, complete genomemetal-dependent phosphohydrolase5e-80299
NC_013523:959625:9745119745119766072097Sphaerobacter thermophilus DSM 20745 chromosome 1, complete genome7TM receptor with intracellular metal dependent phosphohydrolase6e-80298
NC_011978:975333:9753339753339767061374Thermotoga neapolitana DSM 4359, complete genomeMetal dependent phosphohydrolase precursor4e-72273
NC_013895:1086500:1106334110633411084812148Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, completeputative 7TM-HD extracellular9e-71268
NC_000853:1480478:1504570150457015059461377Thermotoga maritima MSB8, complete genomehypothetical protein1e-69265
NC_013642:1317114:1318722131872213200981377Thermotoga naphthophila RKU-10, complete genome7TM receptor with intracellular metal dependent phosphohydrolase2e-69264
NC_010483:1385000:1411679141167914130551377Thermotoga sp. RQ2, complete genomemetal dependent phosphohydrolase2e-69263
NC_009486:1293510:1295118129511812964431326Thermotoga petrophila RKU-1 chromosome, complete genomemetal dependent phosphohydrolase7e-69262
NC_007677:1872459:1889800188980018924272628Salinibacter ruber DSM 13855, complete genomeuncharacterized domain HDIG protein8e-68258
NC_009615:2674631:2681396268139626834352040Parabacteroides distasonis ATCC 8503 chromosome, complete genomemembrane-associated HD superfamily hydrolase4e-54213
NC_009925:5479613:5495563549556354977852223Acaryochloris marina MBIC11017, complete genomemetal dependent phosphohydrolase with 7TM region7e-53209
NC_007513:728324:7519747519747540852112Synechococcus sp. CC9902, complete genomemetal dependent phosphohydrolase1e-42175