Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS




NC_012659: Bacillus anthracis str. A0248, complete genome

NCBI: NC_012659

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
1467893*49056022668Island text3.1545428.172746.6685Neighbours21BLASTN+IslandViewer 467893.gbk
267828969697118683Island text2.7608425.778745.3239Neighbours21BLASTN+678289.gbk
31008028*102661018583Island text2.2724628.783840.5184Neighbours21BLASTN+1008028.gbk
41103737112785124115Island text2.7815626.766539.8151Neighbours21BLASTN1103737.gbk
51334000135622722228Island text1.5253523.504434.9494Neighbours21BLASTN1334000.gbk
61522960154945226493Island text3.958431.652549.0661BLASTN+1522960.gbk
72175867219809922233Island text1.6437722.489133.78Neighbours21BLASTN+2175867.gbk
82715651*273875623106Island text2.3208826.071542.2216Neighbours21BLASTN2715651.gbk
93320933334410423172Island text1.5140323.072731.8248Neighbours21BLASTN+3320933.gbk
103416000344272126722Island text1.5353422.838629.3215Neighbours21BLASTN+3416000.gbk
113464500348209917600Island text1.8125722.774841.5032Neighbours21BLASTN+IslandViewer 3464500.gbk
123579999*359925919261Island text1.5516623.200428.4728Neighbours21BLASTN3579999.gbk
133617000*367368256683Island text1.614620.288235.6133Neighbours21BLASTN3617000.gbk
143692803*371223919437Island text1.6145822.403934.9312Neighbours21BLASTN3692803.gbk
153724729*376569940971Island text1.6362121.41933.7617Neighbours21BLASTN+3724729.gbk
163992684401134918666Island text1.6889826.726235.3945Neighbours21BLASTN3992684.gbk
174116971*413809921129Island text1.6166121.993632.3913Neighbours21BLASTN4116971.gbk
184252000*427358821589Island text1.6131822.872135.6519Neighbours21BLASTN4252000.gbk
194273606*429331719712Island text1.7149822.451533.085Neighbours21BLASTN+4273606.gbk
204399094441839919306Island text1.8126221.741226.8303Neighbours21BLASTN4399094.gbk
214474000*449671722718Island text2.0979222.194638.6544Neighbours21BLASTN4474000.gbk
224507966452671418749Island text1.6260322.302629.8392Neighbours21BLASTN4507966.gbk
234674235469277518541Island text1.5857623.877534.5474Neighbours21BLASTN4674235.gbk
244745053476571420662Island text1.6972823.467531.8566Neighbours21BLASTN4745053.gbk
254853640*487484821209Island text1.5460723.127429.3793Neighbours21BLASTN+IslandViewer 4853640.gbk
264877410*492065343244Island text1.5995422.551932.0045Neighbours21BLASTN+4877410.gbk
275006219503087224654Island text1.8234422.324940.3886Neighbours21BLASTN+5006219.gbk
285031827*507211140285Island text1.6605723.165440.0333Neighbours21BLASTN5031827.gbk
295200831*522352022690Island text2.6463329.43638.825Neighbours21BLASTN5200831.gbk