Pre_GI Gene

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Host: NC_012659 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012659:467893 Bacillus anthracis str. A0248, complete genome

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4678934690831191putative prophage LambdaBa04 major capsid proteinQuickGO ontologyBLASTP
469099469356258hypothetical proteinBLASTP
469353469625273putative prophage LambdaBa04 DNA packaging proteinQuickGO ontologyBLASTP
469622469921300hypothetical proteinBLASTP
469914470270357hypothetical proteinBLASTP
470402470596195hypothetical proteinBLASTP
470597471166570putative prophage LambdaBa04 major tail proteinQuickGO ontologyBLASTP
471171471533363hypothetical proteinBLASTP
471644471757114hypothetical proteinBLASTP
4717754757103936putative prophage LambdaBa04 tape measure proteinQuickGO ontologyBLASTP
475707476516810hypothetical proteinBLASTP
4765314801093579hypothetical proteinBLASTP
480175480336162hypothetical proteinBLASTP
4804054820391635phage minor structural proteinQuickGO ontologyBLASTP
482057482536480hypothetical proteinBLASTP
482631482870240hypothetical proteinBLASTP
482943483086144hypothetical proteinBLASTP
483086483883798putative prophage LambdaBa04 glycosyl hydrolase family 25QuickGO ontologyBLASTP
483937484272336hypothetical proteinBLASTP
484652485389738tRNA pseudouridine synthase AQuickGO ontologyBLASTP
485440485643204hypothetical proteinBLASTP
4857274871301404arginine utilization regulatory protein RocRQuickGO ontologyBLASTP
487404487658255hypothetical proteinBLASTP
4877634891841422amino acid permease family proteinQuickGO ontologyBLASTP
4892804905601281acetylornithine deacetylaseQuickGO ontologyBLASTP