Pre_GI Gene

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Host: NC_012659 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012659:3724729 Bacillus anthracis str. A0248, complete genome

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
372472937260301302cell division protein FtsAQuickGO ontologyBLASTP
37264033727200798cell division protein FtsQQuickGO ontologyBLASTP
37272993728204906UDP-N-acetylenolpyruvoylglucosamine reductaseQuickGO ontologyBLASTP
372826637294171152UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferaseQuickGO ontologyBLASTP
372946637305571092stage V sporulation protein EQuickGO ontologyBLASTP
373064837320001353UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetaseQuickGO ontologyBLASTP
37320013732975975phospho-N-acetylmuramoyl-pentapeptide- transferaseQuickGO ontologyBLASTP
373299837344731476UDP-N-acetylmuramoylalanyl-D-glutamate--2 6-diaminopimelate ligaseQuickGO ontologyBLASTP
373468237365981917sporulation specific penicillin-binding proteinQuickGO ontologyBLASTP
373668037388302151penicillin-binding proteinQuickGO ontologyBLASTP
37388523739214363cell division protein FtsLQuickGO ontologyBLASTP
37392303740162933S-adenosyl-methyltransferase MraWQuickGO ontologyBLASTP
374053337421491617hypothetical proteinBLASTP
374222937431198912-dehydropantoate 2-reductaseQuickGO ontologyBLASTP
37436903744163474hypothetical proteinBLASTP
37441983744704507putative DNA-binding proteinQuickGO ontologyBLASTP
3744833374500617450S ribosomal protein L32QuickGO ontologyBLASTP
37450683745568501hypothetical proteinBLASTP
37459853746581597putative prophage LambdaBa02 lipoproteinQuickGO ontologyBLASTP
37466143747201588hypothetical proteinBLASTP
374717937483601182prophage LambdaBa02 FtsKSpoIIIE family proteinQuickGO ontologyBLASTP
37484763748658183hypothetical proteinBLASTP
37486613748897237hypothetical proteinBLASTP
37491473749353207prophage LambdaBa02 repressor proteinQuickGO ontologyBLASTP
37493573749539183hypothetical proteinBLASTP
37495453750126582hypothetical proteinBLASTP
37501903750894705prophage LambdaBa02 N-acetylmuramoyl-L-alanine amidase PlyLQuickGO ontologyBLASTP
37508943751319426putative prophage LambdaBa02 holinQuickGO ontologyBLASTP
37513243752292969prophage LambdaBa02 site-specific recombinase phage integrase familyQuickGO ontologyBLASTP
37524483752723276prophage LambdaBa02 transcriptional regulator AbrB familyQuickGO ontologyBLASTP
375274837548262079hypothetical proteinBLASTP
375485037568321983phage minor structural proteinQuickGO ontologyBLASTP
375682937583101482hypothetical proteinBLASTP
37583473758958612BLASTP
375902437603761353hypothetical proteinBLASTP
376048137633602880BLASTP
37633763763516141hypothetical proteinBLASTP
37635183763928411hypothetical proteinBLASTP
37639883764572585putative prophage LambdaBa02 major tail proteinQuickGO ontologyBLASTP
37645863764945360hypothetical proteinBLASTP
37649423765379438hypothetical proteinBLASTP
37654153765699285hypothetical proteinBLASTP