Pre_GI Gene

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Host: NC_012659 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012659:5031827 Bacillus anthracis str. A0248, complete genome

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain (96-10355; K1256) is a human isolated from USA. This organism was the first to be shown to cause disease by Dr. Robert Koch, leading to the formulation of Koch's postulates, which were verified by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. Anthrax is not transmitted due to person-to-person contact. The three forms of the disease reflect the sites of infection which include cutaneous (skin), pulmonary (lung), and intestinal. Pulmonary and intestinal infections are often fatal if left untreated. Spores are taken up by macrophages and become internalized into phagolysozomes (membranous compartment) whereupon germination initiates. Bacteria are released into the bloodstream once the infected macrophage lyses whereupon they rapidly multiply, spreading throughout the circulatory and lymphatic systems, a process that results in septic shock, respiratory distress and organ failure. The spores of this pathogen have been used as a terror weapon.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
50308775031830954putative NADH dehydrogenase ubiquinone C subunitQuickGO ontologyBLASTP
50318275032345519NADH dehydrogenase subunit BQuickGO ontologyBLASTP
50323365032704369NADH dehydrogenase subunit AQuickGO ontologyBLASTP
503299550357242730sensory boxGGDEF family proteinQuickGO ontologyBLASTP
50357965036449654hypothetical proteinBLASTP
50364975037288792hypothetical proteinBLASTP
50374105037811402F0F1 ATP synthase subunit epsilonQuickGO ontologyBLASTP
503783250392411410F0F1 ATP synthase subunit betaQuickGO ontologyBLASTP
50393615040221861F0F1 ATP synthase subunit gammaQuickGO ontologyBLASTP
504055750420651509F0F1 ATP synthase subunit alphaQuickGO ontologyBLASTP
50420775042619543F0F1 ATP synthase subunit deltaQuickGO ontologyBLASTP
50426165043122507F0F1 ATP synthase subunit BQuickGO ontologyBLASTP
50432505043468219F0F1 ATP synthase subunit CQuickGO ontologyBLASTP
50435255044244720F0F1 ATP synthase subunit AQuickGO ontologyBLASTP
50442525044644393ATP synthase protein IQuickGO ontologyBLASTP
50446445044868225hypothetical proteinBLASTP
50448955045008114hypothetical proteinBLASTP
50453805046009630uracil phosphoribosyltransferaseQuickGO ontologyBLASTP
504628150475221242serine hydroxymethyltransferaseQuickGO ontologyBLASTP
50477395048329591hypothetical proteinBLASTP
50483785048821444ribose-5-phosphate isomerase BQuickGO ontologyBLASTP
50489185049358441low molecular weight phosphotyrosine protein phosphatase family proteinQuickGO ontologyBLASTP
50496065050103498putative PTS system glucose-specific IIA componentQuickGO ontologyBLASTP
50504905050876387hypothetical proteinBLASTP
50510365051647612hypothetical proteinBLASTP
50518405052118279hypothetical proteinBLASTP
50523495052897549hypothetical proteinBLASTP
505297550540151041sua5yciOyrdCywlC family proteinQuickGO ontologyBLASTP
50541245054582459hypothetical proteinBLASTP
50546325055507876putative stage II sporulation protein RQuickGO ontologyBLASTP
50556115056462852protein-glutamine-N5 methyltransferase release factor-specificQuickGO ontologyBLASTP
505646250575381077peptide chain release factor 1QuickGO ontologyBLASTP
50578005058384585thymidine kinaseQuickGO ontologyBLASTP
5058493505873824650S ribosomal protein L31 type BQuickGO ontologyBLASTP
505914250604131272transcription termination factor RhoQuickGO ontologyBLASTP
50607565061721966fructose 16-bisphosphatase IIQuickGO ontologyBLASTP
506183950631281290UDP-N-acetylglucosamine 1-carboxyvinyltransferaseQuickGO ontologyBLASTP
50634605064317858fructose-bisphosphate aldolaseQuickGO ontologyBLASTP
50645285064896369sporulation initiation phosphotransferase FQuickGO ontologyBLASTP
50650985065622525hypothetical proteinBLASTP
506565450672611608CTP synthetaseQuickGO ontologyBLASTP
50675195068046528DNA-directed RNA polymerase subunit deltaQuickGO ontologyBLASTP
50682015068830630TetR family transcriptional regulatorQuickGO ontologyBLASTP
506889550700341140acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
507005650711861131acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
507126050721118523-hydroxybutyryl-CoA dehydrogenaseQuickGO ontologyBLASTP