Pre_GI Island

Some Help

n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS




NC_003997: Bacillus anthracis str. Ames, complete genome

NCBI: NC_003997

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.



Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
146799349066022668Island text1.5515120.710737.0325Neighbours21BLASTN+IslandViewer 467993.gbk
267426569314918885Island text1.6140622.574226.6415Neighbours21BLASTN+674265.gbk
31007139*102671019572Island text1.5300322.686631.77Neighbours21BLASTN+1007139.gbk
41068000109028722288Island text2.5033622.753538.6222Neighbours21BLASTN1068000.gbk
51334000135620422205Island text1.8252322.704941.0342Neighbours21BLASTN1334000.gbk
61522937154942926493Island text1.556322.958728.4505Neighbours21BLASTN+1522937.gbk
72175843219809922257Island text1.6092823.121435.5768Neighbours21BLASTN+2175843.gbk
82715623*273869223070Island text1.606422.349234.1698Neighbours21BLASTN2715623.gbk
93320906334634325438Island text1.6482521.41933.7617Neighbours21BLASTN+3320906.gbk
103414441344269428254Island text1.7025526.353434.6967Neighbours21BLASTN+3414441.gbk
113462497348209919603Island text1.6156421.431232.6593Neighbours21BLASTN+IslandViewer 3462497.gbk
123579972359923219261Island text1.6241322.501235.8529Neighbours21BLASTN3579972.gbk
133617000*367460757608Island text1.7755922.51833.4331Neighbours21BLASTN3617000.gbk
143692776371221219437Island text1.8136922.528628.152Neighbours21BLASTN3692776.gbk
153724702*376594941248Island text2.1005922.336937.9993Neighbours21BLASTN+IslandViewer 3724702.gbk
163993223401133118109Island text1.6158122.604629.7905Neighbours21BLASTN3993223.gbk
174116944*413809921156Island text1.5807223.740733.887Neighbours21BLASTN4116944.gbk
184252000*427356121562Island text1.7031523.458131.1773Neighbours21BLASTN4252000.gbk
194273579*429175418176Island text1.5403822.86330.1681Neighbours21BLASTN4273579.gbk
204399067441837219306Island text1.6074522.464730.8777Neighbours21BLASTN4399067.gbk
214473973*449668422712Island text1.827622.470840.1206Neighbours21BLASTN4473973.gbk
224507939452668718749Island text1.6597323.387340.2668Neighbours21BLASTN4507939.gbk
234674209469274918541Island text1.6047422.537731.9527NeighboursBLASTN4674209.gbk
244745027476567320647Island text1.5294823.76132.2493Neighbours21BLASTN4745027.gbk
254852332*487482222491Island text1.5965726.240335.4724Neighbours21BLASTN+IslandViewer 4852332.gbk
264876415*492062744213Island text1.6819724.158435.9661Neighbours21BLASTN+4876415.gbk
275006193503084624654Island text1.6190822.817135.5331Neighbours21BLASTN+5006193.gbk
285032969*507209939131Island text1.6563823.837536.0777Neighbours21BLASTN5032969.gbk
295200805*522349422690Island text1.6053523.434534.8337Neighbours21BLASTN5200805.gbk