Query: NC_003997:4399067 Bacillus anthracis str. Ames, complete genome
Start: 4399067, End: 4418372, Length: 19306
Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: This well studied laboratory strain (Porton isolate) is not virulent due to the loss of the two plasmids, pXO1 and pXO2. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_007530:4400152 | 4400152 | 4418499 | 18348 | Bacillus anthracis str. 'Ames Ancestor', complete genome | 0 | 18230 | BLASTN svg | BLASTP svg |
NC_005945:4399756 | 4399756 | 4419061 | 19306 | Bacillus anthracis str. Sterne, complete genome | 0 | 18230 | BLASTN svg | BLASTP svg |
NC_014335:4327584 | 4327584 | 4347099 | 19516 | Bacillus cereus biovar anthracis str. CI chromosome, complete | 0 | 17900 | BLASTN svg | BLASTP svg |
NC_012472:4400420 | 4400420 | 4419210 | 18791 | Bacillus cereus 03BB102, complete genome | 0 | 17740 | BLASTN svg | BLASTP svg |
NC_006274:4448293 | 4448293 | 4466779 | 18487 | Bacillus cereus E33L, complete genome | 0 | 17440 | BLASTN svg | BLASTP svg |
NC_010184:4425676 | 4425676 | 4448719 | 23044 | Bacillus weihenstephanensis KBAB4, complete genome | 0 | 13010 | BLASTN svg | BLASTP svg |
NC_004668:1010610* | 1010610 | 1037133 | 26524 | Enterococcus faecalis V583, complete genome | 3e-76 | 293 | BLASTN svg | BLASTP svg |
NC_010001:404066 | 404066 | 423599 | 19534 | Clostridium phytofermentans ISDg, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_010001:649000* | 649000 | 668901 | 19902 | Clostridium phytofermentans ISDg, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_019978:393351* | 393351 | 412099 | 18749 | Halobacteroides halobius DSM 5150, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_021182:3525523* | 3525523 | 3566737 | 41215 | Clostridium pasteurianum BC1, complete genome | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_015391:1323171* | 1323171 | 1346099 | 22929 | Carnobacterium sp. 17-4 chromosome, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_010694:2189652* | 2189652 | 2219188 | 29537 | Erwinia tasmaniensis, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_015222:523915 | 523915 | 546099 | 22185 | Nitrosomonas sp. AL212 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_012491:5914500* | 5914500 | 5938638 | 24139 | Brevibacillus brevis NBRC 100599, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_014654:188835 | 188835 | 208995 | 20161 | Halanaerobium sp. 'sapolanicus' chromosome, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_011772:1094534 | 1094534 | 1119001 | 24468 | Bacillus cereus G9842, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_010520:3674883* | 3674883 | 3698984 | 24102 | Clostridium botulinum A3 str. Loch Maree, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |