Pre_GI: OUP Neighbours

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Query: NC_016822:1839739 Shigella sonnei 53G, complete genome

D: 37.9198

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

Number of Neighbours: 130




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_011745:1055354*Escherichia coli ED1a chromosome, complete genome78.4559 %Subject ←→ Query30.2164
NC_014500:2525880Dickeya dadantii 3937 chromosome, complete genome75.9375 %Subject ←→ Query30.3147
NC_016863:2721826Salmonella enterica subsp. enterica serovar Typhimurium str. UK-176.7034 %Subject ←→ Query30.7584
NC_013941:5317424Escherichia coli O55:H7 str. CB9615 chromosome, complete genome76.3174 %Subject ←→ Query30.8609
NC_011745:2025725Escherichia coli ED1a chromosome, complete genome79.8683 %Subject ←→ Query31.1649
NC_016810:2719779Salmonella enterica subsp. enterica serovar Typhimurium str76.4553 %Subject ←→ Query31.43
NC_016857:2719779Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/7476.25 %Subject ←→ Query31.43
NC_013971:666730Erwinia amylovora ATCC 49946 chromosome, complete genome76.9118 %Subject ←→ Query31.4537
NC_016856:2773995Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S76.4062 %Subject ←→ Query31.5078
NC_008563:3119284Escherichia coli APEC O1, complete genome81.6513 %Subject ←→ Query31.9127
NC_011742:4962008Escherichia coli S88 chromosome, complete genome75.2298 %Subject ←→ Query32.4611
NC_015737:2050219Clostridium sp. SY8519, complete genome75.3033 %Subject ←→ Query32.545
NC_013353:2134556*Escherichia coli O103:H2 str. 12009, complete genome76.3388 %Subject ←→ Query32.8216
NC_013892:274297Xenorhabdus bovienii SS-2004 chromosome, complete genome77.8094 %Subject ←→ Query32.8965
NC_013941:1014386Escherichia coli O55:H7 str. CB9615 chromosome, complete genome77.2151 %Subject ←→ Query33.1965
NC_011283:942594Klebsiella pneumoniae 342 chromosome, complete genome77.019 %Subject ←→ Query33.3475
NC_007384:1763375Shigella sonnei Ss046, complete genome95.2145 %Subject ←→ Query33.4012
NC_012912:2285778Dickeya zeae Ech1591, complete genome75.6801 %Subject ←→ Query33.4887
NC_011353:921500Escherichia coli O157:H7 str. EC4115 chromosome, complete genome76.6881 %Subject ←→ Query34.5194
NC_011741:256932Escherichia coli IAI1 chromosome, complete genome85.5974 %Subject ←→ Query34.5956
CU928160:256932Escherichia coli IAI1 chromosome, complete genome85.5974 %Subject ←→ Query34.5956
NC_013956:4579759Pantoea ananatis LMG 20103 chromosome, complete genome76.4645 %Subject ←→ Query34.8158
NC_013364:2522888Escherichia coli O111:H- str. 11128, complete genome78.4712 %Subject ←→ Query34.9313
NC_014618:4312295*Enterobacter cloacae SCF1 chromosome, complete genome76.296 %Subject ←→ Query35.071
NC_013008:918215Escherichia coli O157:H7 str. TW14359 chromosome, complete genome78.0484 %Subject ←→ Query35.1897
NC_011353:2892265Escherichia coli O157:H7 str. EC4115 chromosome, complete genome78.413 %Subject ←→ Query35.2611
NC_016831:1865681Salmonella enterica subsp. enterica serovar Gallinarum/pullorum82.9596 %Subject ←→ Query35.6576
NC_016831:687549*Salmonella enterica subsp. enterica serovar Gallinarum/pullorum75.2206 %Subject ←→ Query35.667
NC_011601:756885Escherichia coli O127:H6 str. E2348/69 chromosome, complete genome79.0074 %Subject ←→ Query35.8585
NC_013364:3312379Escherichia coli O111:H- str. 11128, complete genome77.5705 %Subject ←→ Query36.0044
NC_013941:2425233Escherichia coli O55:H7 str. CB9615 chromosome, complete genome77.5827 %Subject ←→ Query36.1047
NC_004631:685357*Salmonella enterica subsp. enterica serovar Typhi Ty2, complete75.0306 %Subject ←→ Query36.1113
NC_016832:687000*Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,75.3523 %Subject ←→ Query36.1337
NC_011601:1077548Escherichia coli O127:H6 str. E2348/69 chromosome, complete genome76.9332 %Subject ←→ Query36.1989
NC_013961:3083816Erwinia amylovora, complete genome76.7555 %Subject ←→ Query36.2172
NC_004431:1352906Escherichia coli CFT073, complete genome80.1899 %Subject ←→ Query36.4239
NC_002695:2158314Escherichia coli O157:H7 str. Sakai, complete genome81.7371 %Subject ←→ Query36.4725
NC_016612:5600177Klebsiella oxytoca KCTC 1686 chromosome, complete genome76.0968 %Subject ←→ Query36.4903
NC_013353:1472506Escherichia coli O103:H2 str. 12009, complete genome80.8517 %Subject ←→ Query36.7127
AP010958:1472506Escherichia coli O103:H2 str. 12009 DNA, complete genome80.8517 %Subject ←→ Query36.7127
NC_011751:1377457Escherichia coli UMN026 chromosome, complete genome79.1544 %Subject ←→ Query36.813
NC_011094:638552Salmonella enterica subsp. enterica serovar Schwarzengrund str77.1324 %Subject ←→ Query36.8525
NC_011353:1195179*Escherichia coli O157:H7 str. EC4115 chromosome, complete genome78.2138 %Subject ←→ Query36.9832
NC_013941:1963523Escherichia coli O55:H7 str. CB9615 chromosome, complete genome80.0429 %Subject ←→ Query36.9893
NC_013364:863209Escherichia coli O111:H- str. 11128, complete genome81.1305 %Subject ←→ Query37.1558
NC_013008:2889743Escherichia coli O157:H7 str. TW14359 chromosome, complete genome78.0055 %Subject ←→ Query37.196
NC_002695:2893951Escherichia coli O157:H7 str. Sakai, complete genome78.5202 %Subject ←→ Query37.275
NC_009648:3476000Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome79.4485 %Subject ←→ Query37.4593
NC_011750:1931384Escherichia coli IAI39 chromosome, complete genome80.242 %Subject ←→ Query37.6581
NC_013361:2169948Escherichia coli O26:H11 str. 11368 chromosome, complete genome81.6513 %Subject ←→ Query37.7614
NC_007385:157516Shigella sonnei Ss046 plasmid pSS_046, complete sequence75.0582 %Subject ←→ Query38.0958
NC_013008:1761165Escherichia coli O157:H7 str. TW14359 chromosome, complete genome80.1501 %Subject ←→ Query38.2113
NC_013361:1896446Escherichia coli O26:H11 str. 11368 chromosome, complete genome81.5472 %Subject ←→ Query38.2296
NC_002655:1909139Escherichia coli O157:H7 EDL933, complete genome79.8131 %Subject ←→ Query38.4667
NC_011353:1761977Escherichia coli O157:H7 str. EC4115 chromosome, complete genome80.2206 %Subject ←→ Query38.5032
NC_011750:919953Escherichia coli IAI39 chromosome, complete genome76.826 %Subject ←→ Query38.6045
NC_011205:329155Salmonella enterica subsp. enterica serovar Dublin str. CT_0202185379.0686 %Subject ←→ Query38.7596
NC_011742:585908Escherichia coli S88 chromosome, complete genome80.2359 %Subject ←→ Query38.828
NC_011353:261220Escherichia coli O157:H7 str. EC4115 chromosome, complete genome81.7923 %Subject ←→ Query38.9884
NC_013008:261226Escherichia coli O157:H7 str. TW14359 chromosome, complete genome81.8107 %Subject ←→ Query39.1965
NC_013941:261094Escherichia coli O55:H7 str. CB9615 chromosome, complete genome82.212 %Subject ←→ Query39.1987
NC_016822:267758Shigella sonnei 53G, complete genome81.7096 %Subject ←→ Query39.2695
NC_011274:1129686Salmonella enterica subsp. enterica serovar Gallinarum str. 287/9181.6667 %Subject ←→ Query39.5488
NC_013361:1593543Escherichia coli O26:H11 str. 11368 chromosome, complete genome77.3591 %Subject ←→ Query40.2481
NC_014121:1822895Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete79.6538 %Subject ←→ Query40.59