Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:685357 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6853576870001644putative ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
687209687703495ecotin precursorQuickGO ontologyBLASTP
688117688608492ferredoxin-type protein NapFQuickGO ontologyBLASTP
688598688861264putative napAB assembly proteinQuickGO ontologyBLASTP
6888586913442487probable nitrate reductaseQuickGO ontologyBLASTP
691351692046696quinol dehydrogenase periplasmic componentQuickGO ontologyBLASTP
692033692902870quinol dehydrogenase membrane componentQuickGO ontologyBLASTP
693018693467450cytochrome c-type protein NapB precursorQuickGO ontologyBLASTP
693477694079603cytochrome c-type protein NapCQuickGO ontologyBLASTP
694100694717618heme exporter protein A1QuickGO ontologyBLASTP
694714695373660heme exporter protein B1QuickGO ontologyBLASTP
695425696162738heme exporter protein C1QuickGO ontologyBLASTP
696159696371213heme exporter protein D1QuickGO ontologyBLASTP
696368696847480cytochrome c-type biogenesis protein E1QuickGO ontologyBLASTP
6968446987751932cytochrome c-type biogenesis protein F1QuickGO ontologyBLASTP
698772699329558thioldisulfide interchange proteinQuickGO ontologyBLASTP
6993267003691044cytochrome c-type biogenesis protein H1QuickGO ontologyBLASTP
700413701060648nitratenitrite response regulator proteinQuickGO ontologyBLASTP
702092702352261hypothetical proteinBLASTP
702544702747204homolog of virulence protein msgAQuickGO ontologyBLASTP
7045107068762367secreted effector proteinQuickGO ontologyBLASTP
70749770757377tRNA-ProQuickGO ontologyBLASTP
7076477094071761putative sulphataseQuickGO ontologyBLASTP
709439709666228hypothetical proteinBLASTP
7098467108531008nucleoid-associated protein NdpAQuickGO ontologyBLASTP