Pre_GI: BLASTN Hits

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Query: NC_009698:2265475 Clostridium botulinum A str. Hall chromosome, complete genome

Start: 2265475, End: 2288716, Length: 23242

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A strain Hall was received at Fort Detrick from Harvard University in 1947. The strain is presumably one from Dr. Ivan Hall's collection, but the exact strain number has been lost. This strain produces high amounts of type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_012563:24660002466000248852922530Clostridium botulinum A2 str. Kyoto, complete genome05654BLASTN svgBLASTP svg
NC_010516:23740002374000239681422815Clostridium botulinum B1 str. Okra, complete genome05580BLASTN svgBLASTP svg
NC_014328:40737144073714410040726694Clostridium ljungdahlii ATCC 49587 chromosome, complete genome3e-120440BLASTN svgBLASTP svg
NC_010516:35931035931038266123352Clostridium botulinum B1 str. Okra, complete genome4e-79303BLASTN svgBLASTP svg
NC_012563:2680246*2680246272077540530Clostridium botulinum A2 str. Kyoto, complete genome4e-73283BLASTN svgBLASTP svg
NC_010520:2585014*2585014262041935406Clostridium botulinum A3 str. Loch Maree, complete genome4e-73283BLASTN svgBLASTP svg
NC_010516:2511035*2511035254588934855Clostridium botulinum B1 str. Okra, complete genome4e-73283BLASTN svgBLASTP svg
NC_010520:15860001586000160832222323Clostridium botulinum A3 str. Loch Maree, complete genome2e-71278BLASTN svgBLASTP svg
NC_012563:519037*51903754582126785Clostridium botulinum A2 str. Kyoto, complete genome1e-42182BLASTN svgBLASTP svg
NC_010520:496500*49650051930622807Clostridium botulinum A3 str. Loch Maree, complete genome3e-37165BLASTN svgBLASTP svg
NC_010516:514000*51400053623322234Clostridium botulinum B1 str. Okra, complete genome2e-34155BLASTN svgBLASTP svg
NC_010520:72531272531274947124160Clostridium botulinum A3 str. Loch Maree, complete genome5e-20107BLASTN svgBLASTP svg
NC_004557:25524182552418257431921902Clostridium tetani E88, complete genome5e-20107BLASTN svgBLASTP svg
NC_012563:37298173729817376659036774Clostridium botulinum A2 str. Kyoto, complete genome3e-18101BLASTN svgBLASTP svg
NC_008593:640000*64000066264322644Clostridium novyi NT, complete genome8e-1693.7BLASTN svgBLASTP svg
NC_020291:22914182291418231430022883Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome8e-1693.7BLASTN svgBLASTP svg
NC_020291:49100049100051106420065Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome8e-1693.7BLASTN svgBLASTP svg
NC_021182:14735351473535149659923065Clostridium pasteurianum BC1, complete genome8e-1693.7BLASTN svgBLASTP svg
NC_010723:37174137174139352221782Clostridium botulinum E3 str. Alaska E43, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010674:37062937062939810727479Clostridium botulinum B str. Eklund 17B, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010520:35800003580000360470824709Clostridium botulinum A3 str. Loch Maree, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010516:35450173545017356809923083Clostridium botulinum B1 str. Okra, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_008593:15131071513107153682423718Clostridium novyi NT, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_013316:89178289178291434722566Clostridium difficile R20291, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_010516:34660003466000348809922100Clostridium botulinum B1 str. Okra, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_010718:1959517*1959517198298623470Natranaerobius thermophilus JW/NM-WN-LF, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_009089:96595996595998833722379Clostridium difficile 630, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_008262:24980002498000252144223443Clostridium perfringens SM101, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_011565:96919896919898909919902Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,3e-0971.9BLASTN svgBLASTP svg
NC_003454:20807052080705210460123897Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete3e-0971.9BLASTN svgBLASTP svg
NC_003454:82280482280484109918296Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete4e-0867.9BLASTN svgBLASTP svg
NC_014393:36509573650957366964218686Clostridium cellulovorans 743B chromosome, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_012225:21989872198987222132922343Brachyspira hyodysenteriae WA1, complete genome3e-0661.9BLASTN svgBLASTP svg