Pre_GI: BLASTP Hits

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Query: NC_009142:5484883:5500645 Saccharopolyspora erythraea NRRL 2338, complete genome

Start: 5500645, End: 5502129, Length: 1485

Host Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008527:611836:6287876287876303101524Lactococcus lactis subsp. cremoris SK11, complete genomeAcyl-coenzyme A synthetase/AMP-(fatty) acid ligase2e-64246
NC_013159:1807599:1817002181700218186331632Saccharomonospora viridis DSM 43017, complete genomeacyl-CoA synthetase (AMP-forming)/AMP-acid ligase II5e-51202
NC_008786:4216152:4237187423718742387071521Verminephrobacter eiseniae EF01-2, complete genomeAMP-dependent synthetase and ligase2e-1687.8
NC_015125:2288487:2308570230857023101171548Microbacterium testaceum StLB037, complete genomeacyl-CoA synthetase (AMP-forming)/AMP-acid ligase II6e-1479.3
NC_015172:1120000:1124267112426711257901524Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeo-succinylbenzoate--CoA ligase4e-1376.6
NC_015859:3346473:3367106336710633686261521Corynebacterium variabile DSM 44702 chromosome, complete genomeacyl-CoA synthetase9e-1375.5
NC_013929:2583849:2586177258617725876701494Streptomyces scabiei 87.22 chromosome, complete genomeAMP-binding synthetase1e-1171.6
NC_014815:841484:8414848414848459774494Micromonospora sp. L5 chromosome, complete genomeamp-dependent synthetase and ligase5e-1169.7
NC_020133:5710661:5726411572641157279341524Mycobacterium liflandii 128FXT, complete genomefatty-acid-CoA ligase FadD34e-1169.7
NC_014335:4566692:4575107457510745765551449Bacillus cereus biovar anthracis str. CI chromosome, completeO-succinylbenzoic acid--CoA ligase4e-1169.7
NC_007958:396439:4170004170004186101611Rhodopseudomonas palustris BisB5, complete genomeAMP-dependent synthetase and ligase1e-1068.6
NC_011969:4556296:4565349456534945667941446Bacillus cereus Q1 chromosome, complete genomeo-succinylbenzoic acid--CoA ligase1e-1068.6
NC_003909:4614789:4621716462171646231611446Bacillus cereus ATCC 10987, complete genomeO-succinylbenzoic acid--CoA ligase1e-1068.2
NC_008595:1844500:1861826186182618633881563Mycobacterium avium 104, complete genomeAMP-dependent synthetase and ligase2e-1067.8
NC_014758:579741:5797415797415812851545Calditerrivibrio nitroreducens DSM 19672 chromosome, completeamp-dependent synthetase and ligase2e-1067.4
NC_015656:2433370:2435573243557324372071635Frankia symbiont of Datisca glomerata chromosome, complete genomeLong-chain-fatty-acid--CoA ligase2e-1067.4
NC_016023:755237:7738307738307753291500Bacillus coagulans 36D1 chromosome, complete genomeAMP-dependent synthetase and ligase3e-1067
CP002797:2025330:2047835204783520494121578Escherichia coli NA114, complete genomeputative thioesterase4e-1066.6
NC_010612:6113155:6131131613113161326541524Mycobacterium marinum M, complete genomefatty-acid-CoA ligase FadD34e-1066.6
NC_016771:4569941:4577238457723845786831446Bacillus cereus NC7401, complete genomeAMP-binding protein6e-1065.9
NC_011658:4616933:4623473462347346249181446Bacillus cereus AH187 chromosome, complete genomeO-succinylbenzoic acid--CoA ligase6e-1065.9
NC_008463:4867504:4875551487555148785352985Pseudomonas aeruginosa UCBPP-PA14, complete genomeputative siderophore biosynthesis enzyme8e-1065.5
NC_011748:2237099:2259594225959422611711578Escherichia coli 55989, complete genomesalicyl-AMP ligase YbtE1e-0965.1
CU928145:2237099:2259594225959422611711578Escherichia coli 55989 chromosome, complete genomesalicyl-AMP ligase YbtE1e-0965.1
NC_011750:1134721:1134721113472111362981578Escherichia coli IAI39 chromosome, complete genomesalicyl-AMP ligase YbtE1e-0965.1
NC_007517:2515870:2540211254021125417641554Geobacter metallireducens GS-15, complete genomeAMP-dependent synthetase and ligase2e-0964.7
NC_003143:2137945:2142992214299221445691578Yersinia pestis CO92, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_004088:2640440:2672229267222926738061578Yersinia pestis KIM, complete genomesalicyl-AMP ligase2e-0964.3
NC_010159:2164500:2169703216970321712801578Yersinia pestis Angola, complete genomeyersiniabactin synthetase, YbtE component2e-0964.3
NC_008253:1938975:1997874199787419994511578Escherichia coli 536, complete genomeyersiniabactin siderophore biosynthetic protein YbtE2e-0964.3
NC_006155:1916426:1921472192147219230491578Yersinia pseudotuberculosis IP 32953, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_011751:2281653:2304148230414823057251578Escherichia coli UMN026 chromosome, complete genomesalicyl-AMP ligase YbtE2e-0964.3
NC_010634:1916000:1921456192145619230331578Yersinia pseudotuberculosis PB1/+, complete genomeAMP-dependent synthetase and ligase2e-0964.3
NC_008150:1420825:1426071142607114276481578Yersinia pestis Antiqua, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_007946:2074098:2096593209659320981701578Escherichia coli UTI89, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_017160:2362002:2393765239376523953421578Yersinia pestis D182038 chromosome, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_017154:2137500:2142560214256021441371578Yersinia pestis D106004 chromosome, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_016845:3448881:3460273346027334618501578Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,yersiniabactin siderophore biosynthetic protein2e-0964.3
NC_009381:1362471:1391630139163013932071578Yersinia pestis Pestoides F chromosome, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_005810:1794490:1799736179973618013131578Yersinia pestis biovar Microtus str. 91001, complete genomeyersiniabactin siderophore biosynthetic protein2e-0964.3
NC_008313:959638:9596389596389611941557Ralstonia eutropha H16 chromosome 1, complete sequenceAcyl-CoA synthetase (AMP-forming)/AMP-acid ligase II3e-0963.5
NC_011745:2168379:2190874219087421924511578Escherichia coli ED1a chromosome, complete genomesalicyl-AMP ligase YbtE4e-0963.5
NC_008563:2094855:2117348211734821189251578Escherichia coli APEC O1, complete genomeyersiniabactin siderophore biosynthetic protein5e-0963.2
NC_011742:2002526:2025021202502120265981578Escherichia coli S88 chromosome, complete genomesalicyl-AMP ligase YbtE5e-0963.2
NC_007925:1448726:1470289147028914718121524Rhodopseudomonas palustris BisB18, complete genomeAMP-dependent synthetase and ligase7e-0962.4
NC_014831:1906691:1942166194216619439921827Thermaerobacter marianensis DSM 12885 chromosome, complete genomeO-succinylbenzoate-CoA ligase9e-0962
NC_008278:5012000:5039859503985950415921734Frankia alni ACN14a, complete genome(2,3-dihydroxybenzoyl)adenylate synthase (2, 3-dihydroxybenzoate-AMP ligase; Dihydroxybenzoic acid-activating enzyme)1e-0861.6
NC_012731:3411161:3422553342255334241301578Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeyersiniabactin siderophore biosynthetic protein1e-0861.6
NC_006512:1942000:1959758195975819614281671Idiomarina loihiensis L2TR, complete genomeAcyl-CoA synthetase2e-0861.2
NC_010170:1324758:1345519134551913470241506Bordetella petrii, complete genomeputative long-chain-fatty-acid--CoA ligase3e-0860.5
NC_020126:4039643:4056045405604540576221578Myxococcus stipitatus DSM 14675, complete genomeAMP-dependent synthetase and ligase3e-0860.5
NC_013757:3897413:3929881392988139314251545Geodermatophilus obscurus DSM 43160, complete genomeAMP-dependent synthetase and ligase4e-0860.1
NC_018581:3202281:3223133322313332243741242Gordonia sp. KTR9 chromosome, complete genomeAcyl-CoA synthetases (AMP-forming)/AMP-acid ligases II4e-0860.1
NC_007530:1068000:1071988107198810735201533Bacillus anthracis str. 'Ames Ancestor', complete genomeacyl-CoA synthase4e-0860.1
NC_009921:5331565:5346623534662353481431521Frankia sp. EAN1pec, complete genomeAMP-dependent synthetase and ligase4e-0860.1
NC_003997:1068000:1071988107198810735201533Bacillus anthracis str. Ames, complete genomeacyl-CoA synthase4e-0860.1
NC_015312:5783366:5800485580048558021731689Pseudonocardia dioxanivorans CB1190 chromosome, complete genomeLong-chain-fatty-acid--CoA ligase5e-0859.7
NC_009434:608765:6806486806486820571410Pseudomonas stutzeri A1501, complete genomelong-chain-fatty-acid-CoA ligase5e-0859.7
NC_008800:2806827:2837840283784028394171578Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,yersiniabactin siderophore biosynthetic protein5e-0859.7
NC_014831:2133060:2161203216120321629511749Thermaerobacter marianensis DSM 12885 chromosome, complete genomeAMP-dependent synthetase and ligase7e-0859.3
NC_008786:2729635:2748653274865327515742922Verminephrobacter eiseniae EF01-2, complete genomeAMP-dependent synthetase and ligase8e-0858.9
NC_015593:463477:4771794771794786721494Sphingobium chlorophenolicum L-1 chromosome chromosome 1, completeLong-chain-fatty-acid--CoA ligase1e-0758.5
NC_015671:1540860:1561806156180615636231818Cellvibrio gilvus ATCC 13127 chromosome, complete genomeAMP-dependent synthetase and ligase2e-0758.2
NC_015576:3976679:4005642400564240071771536Mycobacterium sp. JDM601 chromosome, complete genomefatty-acid-CoA ligase FadD42e-0757.8
NC_004369:437594:4548064548064565451740Corynebacterium efficiens YS-314, complete genomeacyl-CoA synthase2e-0757.8
NC_005957:4311679:4322893432289343245841692Bacillus thuringiensis serovar konkukian str. 97-27, completeacyl-CoA synthase2e-0757.4
NC_011658:4301633:4312847431284743145321686Bacillus cereus AH187 chromosome, complete genomelong-chain-fatty-acid--CoA ligase2e-0757.4
NC_007181:2054663:2067746206774620693711626Sulfolobus acidocaldarius DSM 639, complete genomemedium-chain-fatty-acid-CoA ligase4e-0756.6
NC_012792:547967:5789225789225805591638Variovorax paradoxus S110 chromosome 2, complete genomeAMP-dependent synthetase and ligase4e-0756.6
NC_011969:4235818:4245676424567642473671692Bacillus cereus Q1 chromosome, complete genomelong-chain-fatty-acid--CoA ligase5e-0756.6
NC_014484:371500:3748893748893767121824Spirochaeta thermophila DSM 6192 chromosome, complete genomeAMP-binding enzyme family protein5e-0756.6
NC_004431:2185750:2245422224542222466691248Escherichia coli CFT073, complete genome2,3-dihydroxybenzoate-AMP ligase6e-0756.2
NC_008595:2661019:2675573267557326771741602Mycobacterium avium 104, complete genomeAMP-dependent synthetase and ligase5e-0756.2
NC_015312:681678:6801886801886816811494Pseudonocardia dioxanivorans CB1190 chromosome, complete genomeo-succinylbenzoate--CoA ligase5e-0756.2
NC_015594:410454:4424214424214439891569Sphingobium chlorophenolicum L-1 chromosome chromosome 2, completeo-succinylbenzoate--CoA ligase6e-0755.8
NC_007181:915000:9252859252859268981614Sulfolobus acidocaldarius DSM 639, complete genomeacyl-CoA synthetase7e-0755.8
NC_013892:1890500:19291361929136195807928944Xenorhabdus bovienii SS-2004 chromosome, complete genomeOrnithine racemase1e-0655.5
NC_017075:3165858:3168164316816431697021539Rubrivivax gelatinosus IL144, complete genomeAMP-dependent synthetase and ligase9e-0755.5
NC_007503:1534162:1547668154766815493081641Carboxydothermus hydrogenoformans Z-2901, complete genomelong-chain-fatty-acid--CoA ligase8e-0755.5
NC_018691:2214464:2224910222491022264601551Alcanivorax dieselolei B5 chromosome, complete genomeAMP-dependent synthetase and ligase1e-0654.7
NC_016779:4588000:4597372459737245988201449Bacillus cereus F837/76 chromosome, complete genomeO-succinylbenzoic acid--CoA ligase2e-0654.3
NC_008600:4626464:4639747463974746411951449Bacillus thuringiensis str. Al Hakam, complete genomeo-succinylbenzoic acid--CoA ligase2e-0654.3
NC_015738:1925997:1942757194275719443521596Eggerthella sp. YY7918, complete genomehypothetical protein3e-0653.9
NC_010804:831000:8482878482878498011515Burkholderia multivorans ATCC 17616 chromosome 1, completelong-chain fatty-acid-CoA ligase3e-0653.9
NC_010084:2674972:2674972267497226764861515Burkholderia multivorans ATCC 17616 chromosome 1, completeAMP-dependent synthetase and ligase3e-0653.9
NC_010623:1961685:2002974200297420045691596Burkholderia phymatum STM815 chromosome 2, complete sequenceAMP-dependent synthetase and ligase3e-0653.9
NC_012472:4630485:4643683464368346451311449Bacillus cereus 03BB102, complete genomeAMP-binding protein3e-0653.9
NC_008268:7485710:7497540749754074990601521Rhodococcus sp. RHA1, complete genomeprobable long-chain-fatty-acid--CoA ligase3e-0653.9
NC_003106:91339:99862998621014721611Sulfolobus tokodaii str. 7, complete genomehypothetical fatty-acid--CoA ligase2e-0653.9
NC_011772:4763542:4777195477719547786431449Bacillus cereus G9842, complete genomeO-succinylbenzoate-CoA ligase4e-0653.5
NC_016943:4194002:4206406420640642079171512Blastococcus saxobsidens DD2, complete genomeAMP-dependent synthetase and ligase4e-0653.5
NC_014834:2264108:2297992229799222995481557Rhodopseudomonas palustris DX-1 chromosome, complete genomeAMP-dependent synthetase and ligase5e-0653.1
NC_013282:2582720:2600806260080626024911686Cronobacter turicensis, complete genomeLong-chain-fatty-acid--CoA ligase5e-0653.1
NC_009523:5438000:5457076545707654585961521Roseiflexus sp. RS-1 chromosome, complete genomeAMP-dependent synthetase and ligase5e-0653.1
NC_016023:1083826:1100635110063511022481614Bacillus coagulans 36D1 chromosome, complete genomeAMP-dependent synthetase and ligase5e-0653.1
NC_014228:1929665:19314471931447194943117985Xenorhabdus nematophila ATCC 19061, complete genomeNon-ribosomal peptide synthetase5e-0653.1
NC_014973:1941500:1942658194265819443461689Geobacter sp. M18 chromosome, complete genomeAMP-dependent synthetase and ligase6e-0652.8
NC_007645:2049988:2068130206813020711293000Hahella chejuensis KCTC 2396, complete genomeNon-ribosomal peptide synthetase modules and related protein6e-0652.8
NC_017078:247045:2493922493922510291638Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC1,putative AMP-dependent synthetase/ligase6e-0652.8
NC_007907:2830574:2833553283355328352111659Desulfitobacterium hafniense Y51, complete genomehypothetical protein5e-0652.8
NC_016948:1074034:1094148109414810957791632Mycobacterium intracellulare MOTT-64 chromosome, complete genomelong-chain-fatty-acid--CoA ligase7e-0652.4
NC_008268:3162824:3179531317953131810781548Rhodococcus sp. RHA1, complete genomeprobable AMP-binding acyl-CoA synthetase7e-0652.4
NC_008027:2648560:2661747266174726632881542Pseudomonas entomophila L48, complete genomelong-chain-fatty-acid--CoA ligase8e-0652.4