Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:4566692 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4566692456770810172-dehydro-3-deoxygluconokinaseQuickGO ontologyBLASTP
45677014568456756hypothetical proteinBLASTP
456845345695621110L-seryl-tRNASec selenium transferaseQuickGO ontologyBLASTP
456954045706401101amidohydrolase family proteinQuickGO ontologyBLASTP
45710044571864861D-alanyl-D-alanine carboxypeptidaseQuickGO ontologyBLASTP
457194745730531107sensor histidine kinaseQuickGO ontologyBLASTP
45730464573744699DNA-binding response regulatorQuickGO ontologyBLASTP
457400045751061107o-succinylbenzoate-CoA synthaseQuickGO ontologyBLASTP
457510745765551449O-succinylbenzoic acid--CoA ligaseQuickGO ontologyBLASTP
45767554577573819naphthoate synthaseQuickGO ontologyBLASTP
45776434578455813hydrolaseQuickGO ontologyBLASTP
4578452458020617552-oxoglutarate decarboxylaseQuickGO ontologyBLASTP
458020345815971395menaquinone-specific isochorismate synthaseQuickGO ontologyBLASTP
4581792458274595414-dihydroxy-2-naphthoate octaprenyltransferaseQuickGO ontologyBLASTP
45828554583586732DnaK suppressor proteinQuickGO ontologyBLASTP
45836314583831201cold shock proteinQuickGO ontologyBLASTP
45841584584940783hypothetical proteinBLASTP