Pre_GI Gene

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Host: NC_016845 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016845:3448881 Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
344888134583729492High-molecular-weight nonribosomal peptidepolyketide synthetase 1 HMWP1QuickGO ontologyBLASTP
345836934594691101irp3 protein yersiniabactin siderophore biosynthetic proteinQuickGO ontologyBLASTP
34595323460269738putative thioesterase YbtTQuickGO ontologyBLASTP
346027334618501578yersiniabactin siderophore biosynthetic proteinQuickGO ontologyBLASTP
346198134640022022pesticinyersiniabactin TonB-dependent receptorQuickGO ontologyBLASTP
34648743465800927hypothetical proteinBLASTP
34663143466895582hypothetical proteinBLASTP
34673373467465129hypothetical proteinBLASTP
34680343468267234hypothetical proteinBLASTP
34683403469050711putative type IV secretory pathway VirB1 componentQuickGO ontologyBLASTP
34691643469343180hypothetical proteinBLASTP
346935634720942739putative type IV secretory pathway VirB4 componentQuickGO ontologyBLASTP
34721123472819708hypothetical proteinBLASTP
347307334741461074hypothetical proteinBLASTP
34742193474338120hypothetical proteinBLASTP
34743683475051684type IV secretion system VirB8 componentQuickGO ontologyBLASTP
34750483475956909type IV secretory pathway VirB9 componentQuickGO ontologyBLASTP
347600034772501251type IV secretory pathway VirB10 componentQuickGO ontologyBLASTP
347724034782651026type IV secretory pathway VirB11 componentQuickGO ontologyBLASTP
34791933479348156hypothetical proteinBLASTP
348005834819171860putative MobB mobilization proteinQuickGO ontologyBLASTP
34819273482673747putative MobC mobilization proteinQuickGO ontologyBLASTP
34828663483810945putative Antirestriction protein ardCQuickGO ontologyBLASTP
34848163485811996hypothetical proteinBLASTP
348580834868961089hypothetical proteinBLASTP
34871333487387255hypothetical proteinBLASTP
348738434892641881hypothetical proteinBLASTP
348954834905671020hypothetical proteinBLASTP