Pre_GI Gene

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Host: NC_008595 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008595:2661019 Mycobacterium avium 104, complete genome

Host Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
26610192661813795carveol dehydrogenaseQuickGO ontologyBLASTP
26618232662359537thioesterase family proteinQuickGO ontologyBLASTP
266252426649442421caibbaif family proteinQuickGO ontologyBLASTP
26649492665632684transcriptional regulator TetR family proteinQuickGO ontologyBLASTP
26657752666005231hypothetical proteinBLASTP
266599526672691275transposase Mutator family proteinQuickGO ontologyBLASTP
26673752668328954amidohydrolase 2QuickGO ontologyBLASTP
266836926695321164thiolaseQuickGO ontologyBLASTP
26695292669984456protein of unknown function DUF35QuickGO ontologyBLASTP
26704792671048570putative transcription regulatorQuickGO ontologyBLASTP
267132426724031080hypothetical protein
267270126738731173cytochrome p450QuickGO ontologyBLASTP
267389926747388403-hydroxyisobutyrate dehydrogenaseQuickGO ontologyBLASTP
26748072675556750carveol dehydrogenaseQuickGO ontologyBLASTP
267557326771741602AMP-dependent synthetase and ligaseQuickGO ontologyBLASTP
26771712677707537hypothetical proteinBLASTP
26777582678681924short chain dehydrogenaseQuickGO ontologyBLASTP
26786782679112435hypothetical proteinBLASTP
26791062679909804enoyl CoA hydrataseQuickGO ontologyBLASTP
267990626811801275cytochrome P450QuickGO ontologyBLASTP
268132426824061083oxidoreductase family protein NAD-binding Rossmann fold proteinQuickGO ontologyBLASTP