Pre_GI Gene

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Host: NC_011658 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011658:4616933 Bacillus cereus AH187 chromosome, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was isolated from the vomit of a person having eaten cooked rice by the Public Health Laboratory Service (PHLS), London, UK. The isolate was associated with an emetic outbreak in 1972. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
461693346180361104putative pyridoxal phosphate-dependent enzymeQuickGO ontologyBLASTP
461801446191141101dihydroorotaseQuickGO ontologyBLASTP
46194104620270861D-alanyl-D-alanine carboxypeptidase family proteinQuickGO ontologyBLASTP
462035346214591107sensor histidine kinaseQuickGO ontologyBLASTP
46214524622150699DNA-binding response regulatorQuickGO ontologyBLASTP
462236646234721107N-acylamino acid racemaseQuickGO ontologyBLASTP
462347346249181446O-succinylbenzoic acid--CoA ligaseQuickGO ontologyBLASTP
46251384625257120hypothetical proteinBLASTP
46252364626054819naphthoate synthaseQuickGO ontologyBLASTP
46261244626936813alphabeta fold family hydrolaseQuickGO ontologyBLASTP
4626933462868717552-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthaseQuickGO ontologyBLASTP
462868446300781395menaquinone-specific isochorismate synthaseQuickGO ontologyBLASTP
4630273463122695414-dihydroxy-2-naphthoate octaprenyltransferaseQuickGO ontologyBLASTP
46313364632067732DksATraR family DNA binding proteinQuickGO ontologyBLASTP
46321124632312201cold shock protein CspDQuickGO ontologyBLASTP
46327044633486783hypothetical proteinBLASTP
46335104634280771MerR family transcriptional regulatorQuickGO ontologyBLASTP
46344214635143723lipase family proteinQuickGO ontologyBLASTP
463548846378962409glycogen phosphorylaseQuickGO ontologyBLASTP