Pre_GI Gene

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Host: NC_008595 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008595:1844500 Mycobacterium avium 104, complete genome

Host Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
184455018459381389acyltransferase wsdgatmgat subfamily proteinQuickGO ontologyBLASTP
18459911846974984dihydroflavonol-4-reductase family proteinQuickGO ontologyBLASTP
18469711847801831enoyl-CoA hydrataseisomeraseQuickGO ontologyBLASTP
18478281848472645hypothetical proteinBLASTP
184849418497261233amidohydrolase family proteinQuickGO ontologyBLASTP
18498501850479630transcriptional regulator TetR family proteinQuickGO ontologyBLASTP
18505821850827246MFS transporterQuickGO ontology
18508661851156291transposaseQuickGO ontologyBLASTP
185127218525461275transposase Mutator family proteinQuickGO ontologyBLASTP
18525401853325786transposaseQuickGO ontologyBLASTP
185361418547201107oxygenase KshAQuickGO ontologyBLASTP
18548511855483633transcriptional regulator TetR family proteinQuickGO ontology
18556091856607999iron-sulfur cluster-binding protein Rieske family proteinQuickGO ontologyBLASTP
18566511857391741hypothetical proteinBLASTP
18584261858851426hypothetical proteinBLASTP
185885318600401188beta-ketoadipyl CoA thiolaseQuickGO ontologyBLASTP
18601511860609459MaoC domain proteinQuickGO ontologyBLASTP
186060918618201212DitF proteinQuickGO ontologyBLASTP
186182618633881563AMP-dependent synthetase and ligaseQuickGO ontologyBLASTP
18633851863852468hypothetical proteinBLASTP
18639011864281381hypothetical proteinBLASTP