Pre_GI: BLASTP Hits

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Query: NC_005956:1402500:1423452 Bartonella henselae str. Houston-1, complete genome

Start: 1423452, End: 1424366, Length: 915

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005955:1166521:118600111860011186915915Bartonella quintana str. Toulouse, complete genomehypothetical protein2e-155548
NC_012846:1741000:176285217628521763769918Bartonella grahamii as4aup, complete genomeputative rhodanese-related sulfurtransferase protein3e-154544
NC_008783:1101973:112046311204631121380918Bartonella bacilliformis KC583, complete genomerhodanese-like domain protein1e-141502
NC_014932:1232346:127800112780011278918918Bartonella clarridgeiae 73, complete genomehypothetical protein8e-140496
NC_020300:1241968:125805812580581258975918Bartonella australis Aust/NH1, complete genomeputative rhodanese-related sulfurtransferase protein7e-133473
NC_014733:2363838:236948323694832370442960Methylovorus sp. MP688 chromosome, complete genomerhodanese domain protein1e-91336
NC_012969:2476318:247871924787192479717999Methylovorus glucosetrophus SIP3-4 chromosome, complete genomeRhodanese domain-containing protein5e-91334
NC_007947:2447635:247631624763162477287972Methylobacillus flagellatus KT, complete genomeRhodanese-like protein5e-88324
NC_010475:1563578:157834315783431579239897Synechococcus sp. PCC 7002, complete genomeRhodanese-like sulfurtransferase2e-82305
NC_010677:1296000:131462913146291315615987Francisella tularensis subsp. mediasiatica FSC147, complete genomeputative rhodanese, sulfurtransferase4e-82304
NC_005071:1111605:113801511380151138947933Prochlorococcus marinus str. MIT 9313, complete genomehypothetical protein3e-68258
NC_007797:1016456:102454910245491025388840Anaplasma phagocytophilum HZ, complete genomerhodanese domain protein6e-63241
NC_018643:641360:659028659028659936909Alpha proteobacterium HIMB5 chromosome, complete genomerhodanese-like protein1e-62240
NC_003103:164972:166684166684167427744Rickettsia conorii str. Malish 7, complete genomehypothetical protein9e-58224
NC_016929:141972:147993147993148742750Rickettsia canadensis str. CA410 chromosome, complete genomehypothetical protein8e-58224
NC_009879:141000:147028147028147777750Rickettsia canadensis str. McKiel, complete genomehypothetical protein3e-57222
NC_016915:162841:169296169296170039744Rickettsia rickettsii str. Hlp#2 chromosome, complete genomehypothetical protein3e-57222
NC_016930:165376:167064167064167807744Rickettsia philipii str. 364D chromosome, complete genomehypothetical protein7e-57221
NC_006576:2328427:235127123512712352080810Synechococcus elongatus PCC 6301, complete genomehypothetical protein5e-57221
NC_009882:167350:169030169030169773744Rickettsia rickettsii str. 'Sheila Smith', complete genomehypothetical protein4e-57221
NC_010263:167450:169123169123169866744Rickettsia rickettsii str. Iowa, complete genomerhodanese-related sulfurtransferase4e-57221
NC_016908:167423:169103169103169846744Rickettsia rickettsii str. Colombia chromosome, complete genomehypothetical protein4e-57221
NC_016911:167398:169071169071169814744Rickettsia rickettsii str. Hauke chromosome, complete genomehypothetical protein4e-57221
NC_016914:167537:169210169210169953744Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein4e-57221
NC_009881:166500:172853172853173596744Rickettsia akari str. Hartford, complete genomehypothetical protein5e-56218
NC_009883:277409:279122279122279868747Rickettsia bellii OSU 85-389, complete genomehypothetical protein6e-56218
NC_000963:141500:148519148519149262744Rickettsia prowazekii str. Madrid E, complete genomehypothetical protein5e-55214
NC_017048:484000:490683490683491426744Rickettsia prowazekii str. GvV257 chromosome, complete genomehypothetical protein5e-55214
NC_017049:140000:146718146718147461744Rickettsia prowazekii str. Chernikova chromosome, complete genomehypothetical protein5e-55214
NC_017050:141500:148517148517149260744Rickettsia prowazekii str. Katsinyian chromosome, complete genomehypothetical protein5e-55214
NC_017051:140000:146722146722147465744Rickettsia prowazekii str. Dachau chromosome, complete genomehypothetical protein5e-55214
NC_017056:141500:148527148527149270744Rickettsia prowazekii str. BuV67-CWPP chromosome, complete genomehypothetical protein5e-55214
NC_017057:142000:148739148739149482744Rickettsia prowazekii str. RpGvF24 chromosome, complete genomehypothetical protein5e-55214
NC_007798:213069:216393216393217301909Neorickettsia sennetsu str. Miyayama, complete genomerhodanese domain protein1e-54213
NC_017066:140853:149053149053149796744Rickettsia typhi str. TH1527 chromosome, complete genomehypothetical protein3e-54212
NC_017062:141270:149470149470150213744Rickettsia typhi str. B9991CWPP chromosome, complete genomehypothetical protein3e-54212
NC_006142:140853:149053149053149796744Rickettsia typhi str. Wilmington, complete genomehypothetical protein3e-54212
NC_013009:225722:227614227614228498885Neorickettsia risticii str. Illinois, complete genomerhodanese domain protein2e-51202
NC_010793:1695716:171276517127651713514750Orientia tsutsugamushi str. Ikeda, complete genomePredicted sulfurtransferase8e-49194
NC_009488:767525:785940785940786689750Orientia tsutsugamushi str. Boryong, complete genomesulfurtransferase1e-47190
NC_010084:1054000:1055060105506010560791020Burkholderia multivorans ATCC 17616 chromosome 1, completerhodanese superfamily protein1e-45183
NC_006270:3418097:341809734180973419065969Bacillus licheniformis ATCC 14580, complete genomehypothetical protein5e-44178
NC_006322:3418268:341826834182683419236969Bacillus licheniformis ATCC 14580, complete genomehypothetical protein5e-44178
NC_004193:375416:601147601147602118972Oceanobacillus iheyensis HTE831, complete genomehypothetical protein1e-43177
NC_002953:2773000:277524127752412776197957Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein4e-40165
NC_003923:2794686:279590127959012796857957Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein4e-40165
NC_004461:245768:261489261489262451963Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein1e-39163
NC_019904:2095971:211581621158162116799984Echinicola vietnamensis DSM 17526 chromosome, complete genomesulfurtransferase5e-37155
NC_010688:2781624:278162427816242782385762Xanthomonas campestris pv. campestris, complete genomehypothetical protein2e-36152
NC_010830:1171781:117556011755601176516957Candidatus Amoebophilus asiaticus 5a2, complete genomehypothetical protein3e-35149
NC_014924:1701952:171994517199451720727783Pseudoxanthomonas suwonensis 11-1 chromosome, complete genomeRhodanese domain protein2e-32139
NC_020156:1565500:1586108158610815871421035Nonlabens dokdonensis DSW-6, complete genomesulfurtransferase1e-29130
NC_016510:1958453:1971686197168619730561371Flavobacterium columnare ATCC 49512 chromosome, complete genomerhodanese domain-containing protein2e-27123
NC_013174:650986:656022656022656936915Jonesia denitrificans DSM 20603, complete genomeRhodanese domain protein9e-27120
NC_020302:3014483:301511030151103016024915Corynebacterium halotolerans YIM 70093 = DSM 44683, completeputative rhodanese-related sulfurtransferase7e-26118
NC_012912:1788308:1834173183417318352341062Dickeya zeae Ech1591, complete genomeRhodanese domain protein1e-25117
NC_015968:1709680:1730549173054917315981050Enterobacter asburiae LF7a chromosome, complete genomehypothetical protein8e-25114
NC_003143:2741478:2750905275090527519721068Yersinia pestis CO92, complete genomehypothetical protein8e-25114
NC_017168:2999514:3010461301046130115281068Yersinia pestis A1122 chromosome, complete genomeputative rhodanese-related sulfurtransferase8e-25114
NC_005810:2508671:2520829252082925219501122Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein7e-25114
NC_004088:1909880:1919805191980519209261122Yersinia pestis KIM, complete genomehypothetical protein7e-25114
NC_014306:1810548:1825626182562618266751050Erwinia billingiae Eb661, complete genomehypothetical protein8e-24111
NC_020211:2012480:2017792201779220188591068Serratia marcescens WW4, complete genomeputative rhodanese-related sulfurtransferase2e-23110
NC_008150:2173708:218271521827152183500786Yersinia pestis Antiqua, complete genomehypothetical protein9e-23107