Pre_GI Gene

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Host: NC_017066 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017066:140853 Rickettsia typhi str. TH1527 chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
140853141356504F0F1 ATP synthase subunit BQuickGO ontologyBLASTP
1432151442791065putative nucleoside-diphosphate-sugar epimeraseQuickGO ontologyBLASTP
144279145235957ATP-binding protein MrpQuickGO ontologyBLASTP
1453361463701035protease activity modulator protein HflKQuickGO ontologyBLASTP
146522147382861protease activity modulator protein HflCQuickGO ontologyBLASTP
1473981489541557serine proteaseQuickGO ontologyBLASTP
149053149796744hypothetical proteinBLASTP
149938150312375succinate dehydrogenase cytochrome b-556 subunitQuickGO ontologyBLASTP
150470150847378succinate dehydrogenase hydrophobic membrane anchor proteinQuickGO ontologyBLASTP
1509871527771791succinate dehydrogenase flavoprotein subunitQuickGO ontologyBLASTP
152913153569657glutamine transport system permease protein GlnPQuickGO ontologyBLASTP
15373015411939030S ribosomal protein S12QuickGO ontologyBLASTP
15415215463448330S ribosomal protein S7QuickGO ontologyBLASTP
1546471567462100elongation factor GQuickGO ontologyBLASTP
15689015696576tRNA-TrpQuickGO ontologyBLASTP
157133157333201preprotein translocase subunit SecEQuickGO ontologyBLASTP
157349157927579transcription antitermination protein NusGQuickGO ontologyBLASTP
15810515854243850S ribosomal protein L11QuickGO ontologyBLASTP
15854515925871450S ribosomal protein L1QuickGO ontologyBLASTP
15934815985751050S ribosomal protein L10QuickGO ontologyBLASTP
16003816041537850S ribosomal protein L7L12QuickGO ontologyBLASTP
1612401653644125DNA-directed RNA polymerase subunit betaQuickGO ontologyBLASTP
1656661697844119DNA-directed RNA polymerase subunit betaQuickGO ontologyBLASTP
1708171723191503multifunctional aminopeptidase AQuickGO ontologyBLASTP
172414173208795hypothetical proteinBLASTP
173310173744435hypothetical proteinBLASTP
1738161756331818aspartyl-tRNA synthetaseQuickGO ontologyBLASTP
1758871780102124hypothetical proteinBLASTP
178110178820711hypothetical proteinBLASTP
179021179740720dihydrodipicolinate reductaseQuickGO ontologyBLASTP
180003180488486hypothetical proteinBLASTP
180473181198726glutamine-binding periplasmic protein GlnHQuickGO ontologyBLASTP
1813631828141452aspartylglutamyl-tRNA amidotransferase subunit BQuickGO ontologyBLASTP
1829691844501482aspartylglutamyl-tRNA amidotransferase subunit AQuickGO ontologyBLASTP