Pre_GI Gene

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Host: NC_012125 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012125:2938519 Salmonella enterica subsp. enterica serovar Paratyphi C strain

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The genome of this strain harbors a large pathogenicity island, SPI7, with genes coding for the Vi (virulence) antigen and other genes potentially associated with virulence. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
293851929405822064transcriptional activator of the formate hydrogenlyase systemQuickGO ontologyBLASTP
29406442940988345hypothetical proteinBLASTP
29411702942087918iron transport protein periplasmic-binding proteinQuickGO ontologyBLASTP
29420842942905822iron ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
29429022943762861iron transport protein inner membrane componentQuickGO ontologyBLASTP
29437532944601849iron transport protein inner membrane componentQuickGO ontologyBLASTP
29448782945633756AraC family transcriptional regulatorQuickGO ontologyBLASTP
29460182946905888AraC family transcriptional regulatorQuickGO ontologyBLASTP
29472502947612363cytoplasmic proteinQuickGO ontologyBLASTP
29476992948379681oxygen-regulated invasion proteinQuickGO ontologyBLASTP
29483362948839504oxygen-regulated invasion proteinQuickGO ontologyBLASTP
29489072949665759pathogenicity 1 island effector proteinQuickGO ontologyBLASTP
29496622949904243cytoplasmic cell invasion proteinQuickGO ontologyBLASTP
29499862950228243pathogenicity 1 island effector proteinQuickGO ontologyBLASTP
295025329514311179pathogenicity 1 island effector proteinQuickGO ontologyBLASTP
29517472952676930AraC family transcriptional regulatorQuickGO ontologyBLASTP
295376729554281662invasion protein regulatorQuickGO ontologyBLASTP
29554462955928483cell invasion proteinQuickGO ontologyBLASTP
295598229575501569tyrosine phosphataseQuickGO ontologyBLASTP
29576002957992393secretion chaperoneQuickGO ontologyBLASTP
29580192958243225hypothetical proteinBLASTP
29583232958571249acyl carrier proteinQuickGO ontologyBLASTP
295859029606022013pathogenicity island 1 effector proteinQuickGO ontologyBLASTP
296066629616971032cell invasion proteinQuickGO ontologyBLASTP
296176829629971230pathogenicity island 1 effector proteinQuickGO ontologyBLASTP
296302529648061782pathogenicity island 1 effector proteinQuickGO ontologyBLASTP
29648092965306498hypothetical proteinBLASTP
296544429665141071surface presentation of antigens protein SpaSQuickGO ontologyBLASTP
29665012967292792virulence associated secretory proteinQuickGO ontologyBLASTP
29672962967556261virulence associated secretory proteinQuickGO ontologyBLASTP
29675822968256675surface presentation of antigens protein SpaPQuickGO ontologyBLASTP
29682462969145900surface presentation of antigens protein SpaOQuickGO ontologyBLASTP
296915729701671011antigen presentation protein SpaNQuickGO ontologyBLASTP
29701672970610444virulence-associated secretory proteinQuickGO ontologyBLASTP
297058829718831296ATP synthase SpaLQuickGO ontologyBLASTP
29718802972287408virulence-associated secretory proteinQuickGO ontologyBLASTP
297231129743682058virulence associated secretory proteinQuickGO ontologyBLASTP
297439329755111119cell invasion proteinQuickGO ontologyBLASTP
297550829771061599virulence-associated secretory proteinQuickGO ontologyBLASTP
29771932977942750invasion proteinQuickGO ontologyBLASTP
29782992978742444cell adheranceinvasion proteinQuickGO ontologyBLASTP
29796142979904291hypothetical proteinBLASTP
29799012980428528hypothetical proteinBLASTP
29805012980677177cytoplasmic proteinQuickGO ontologyBLASTP
29810542981710657serinethreonine-specific protein phosphatase 2QuickGO ontologyBLASTP
29819552982449495hypothetical proteinBLASTP
29824762983144669hypothetical proteinBLASTP
29835672983704138transposaseQuickGO ontologyBLASTP
29837192984129411cytoplasmic proteinQuickGO ontologyBLASTP
298428729868542568DNA mismatch repair protein MutSQuickGO ontologyBLASTP
29869102987290381cytoplasmic proteinQuickGO ontologyBLASTP
298728729884921206membrane transport proteinQuickGO ontologyBLASTP
29885802989512933LysR family transcriptional regulatorQuickGO ontologyBLASTP
298955429910501497permeaseQuickGO ontologyBLASTP
29910472991997951hypothetical proteinBLASTP