Pre_GI: BLASTP Hits

Subject	Start	End	Length	Subject Host Description	CDS description	E-value	Bit score
NC_015391:1013608:1032931	1032931	1033743	813	Carnobacterium sp. 17-4 chromosome, complete genome	putative phosphatase	8e-33	139
NC_015975:923812:928139	928139	928945	807	Lactobacillus ruminis ATCC 27782 chromosome, complete genome	hydrolase, HAD superfamily	8e-29	125
NC_021175:1291707:1312603	1312603	1313415	813	Streptococcus oligofermentans AS 1.3089, complete genome	hypothetical protein	3e-23	107
NC_011725:1182000:1186777	1186777	1187586	810	Bacillus cereus B4264 chromosome, complete genome	haloacid dehalogenase-like family hydrolase	9e-22	102
NC_020210:661236:680566	680566	681372	807	Geobacillus sp. GHH01, complete genome	putative Cof-like hydrolase	7e-21	99.8
NC_016593:762216:795790	795790	796596	807	Geobacillus thermoleovorans CCB_US3_UF5 chromosome, complete	phosphatase yitU	9e-21	99.4
NC_009615:1305678:1307590	1307590	1308396	807	Parabacteroides distasonis ATCC 8503 chromosome, complete genome	haloacid dehalogenase	1e-15	82.4
NC_013171:228356:249644	249644	250441	798	Anaerococcus prevotii DSM 20548, complete genome	Cof-like hydrolase	1e-13	75.5
NC_017243:2778427:2795157	2795157	2795948	792	Brachyspira intermedia PWS/A chromosome, complete genome	hydrolase, HAD superfamily	2e-13	75.1
NC_012470:678661:687445	687445	688272	828	Streptococcus equi subsp. zooepidemicus, complete genome	haloacid dehalogenase-like hydrolase	3e-13	74.3
NC_014958:1335650:1351939	1351939	1352778	840	Deinococcus maricopensis DSM 21211 chromosome, complete genome	Cof-like hydrolase	1e-12	72.4
NC_015391:1013608:1021680	1021680	1022489	810	Carnobacterium sp. 17-4 chromosome, complete genome	hydrolase, haloacid dehalogenase-like family	1e-12	72
NC_014364:2904443:2906465	2906465	2907304	840	Spirochaeta smaragdinae DSM 11293 chromosome, complete genome	Cof-like hydrolase	6e-12	69.7
NC_013741:687546:703024	703024	703683	660	Archaeoglobus profundus DSM 5631, complete genome	SPP-like hydrolase	8e-12	69.7
NC_014652:666227:667952	667952	668791	840	Caldicellulosiruptor hydrothermalis 108 chromosome, complete	cof-like hydrolase	2e-11	68.2
NC_015949:2002752:2020521	2020521	2021360	840	Caldicellulosiruptor lactoaceticus 6A chromosome, complete genome	Cof-like hydrolase	6e-11	66.6
NC_013171:228356:250441	250441	251250	810	Anaerococcus prevotii DSM 20548, complete genome	Cof-like hydrolase	1e-10	65.9
NC_004668:2938000:2938749	2938749	2939525	777	Enterococcus faecalis V583, complete genome	hydrolase, haloacid dehalogenase-like family	1e-10	65.9
NC_017316:2466244:2466854	2466854	2467633	780	Enterococcus faecalis OG1RF chromosome, complete genome	hydrolase	1e-10	65.9
NC_016610:61661:62478	62478	63710	1233	Tannerella forsythia ATCC 43037 chromosome, complete genome	cof family hydrolase	2e-10	64.7
NC_013406:7024149:7038556	7038556	7039320	765	Paenibacillus sp. Y412MC10 chromosome, complete genome	Cof-like hydrolase	2e-10	64.7
NC_008528:331260:353818	353818	354633	816	Oenococcus oeni PSU-1, complete genome	Predicted hydrolase of the HAD superfamily	4e-10	63.9
NC_008532:469888:479842	479842	480663	822	Streptococcus thermophilus LMD-9, complete genome	Predicted hydrolase of the HAD superfamily	5e-10	63.5
NC_006448:465656:475588	475588	476445	858	Streptococcus thermophilus LMG 18311, complete genome	hypothetical protein	6e-10	63.5
NC_014614:1259236:1259236	1259236	1260054	819	Clostridium sticklandii, complete genome	Cof-like hydrolase	1e-09	62.4
NC_004337:3590323:3875804	3875804	3876616	813	Shigella flexneri 2a str. 301, complete genome	hypothetical protein	1e-09	62.4
NC_014039:2320307:2323428	2323428	2324201	774	Propionibacterium acnes SK137 chromosome, complete genome	HAD hydrolase, family IIB	2e-09	61.6
NC_010723:3133302:3146575	3146575	3147402	828	Clostridium botulinum E3 str. Alaska E43, complete genome	phosphatase YidA	2e-09	61.6
NC_009253:3317533:3317533	3317533	3318339	807	Desulfotomaculum reducens MI-1 chromosome, complete genome	cof family hydrolase	2e-09	61.6
NC_016845:1773416:1775607	1775607	1776419	813	Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,	putative hydrolase	2e-09	61.2
NC_016516:2314115:2317253	2317253	2318008	756	Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete	HAD superfamily hydrolase	2e-09	61.2
NC_016511:2321999:2326394	2326394	2327149	756	Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete	HAD superfamily hydrolase	2e-09	61.2
NC_016612:3361802:3366112	3366112	3366927	816	Klebsiella oxytoca KCTC 1686 chromosome, complete genome	phosphatase YbjI	2e-09	61.2
NC_016512:2322598:2325718	2325718	2326491	774	Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete	HAD superfamily hydrolase	2e-09	61.2
NC_006085:2384892:2388012	2388012	2388785	774	Propionibacterium acnes KPA171202, complete genome	hydrolase (HAD superfamily)	2e-09	61.2
NC_017337:610000:615526	615526	616395	870	Staphylococcus aureus subsp. aureus ED133 chromosome, complete	haloacid dehalogenase-like family hydrolase	4e-09	60.8
NC_007622:567500:571874	571874	572743	870	Staphylococcus aureus RF122, complete genome	hypothetical protein	4e-09	60.5
NC_017342:2733215:2748743	2748743	2749612	870	Staphylococcus aureus subsp. aureus TCH60 chromosome, complete	HAD superfamily hydrolase	4e-09	60.5
NC_002952:610462:614544	614544	615413	870	Staphylococcus aureus subsp. aureus MRSA252, complete genome	putative haloacid dehalogenase-like hydrolase	4e-09	60.5
NC_008800:2695977:2708773	2708773	2709585	813	Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,	putative hydrolase	5e-09	60.5
NC_014551:2510000:2557833	2557833	2558252	420	Bacillus amyloliquefaciens DSM 7, complete genome	hypothetical protein	5e-09	60.5
NC_014364:1990000:2004700	2004700	2005506	807	Spirochaeta smaragdinae DSM 11293 chromosome, complete genome	Cof-like hydrolase	6e-09	60.1
NC_015602:1143038:1143038	1143038	1143853	816	Lactobacillus kefiranofaciens ZW3 chromosome, complete genome	hypothetical protein	6e-09	60.1
NC_015172:1621223:1626769	1626769	1627587	819	Syntrophobotulus glycolicus DSM 8271 chromosome, complete genome	Cof-like hydrolase	5e-09	60.1
NC_015496:2279829:2285849	2285849	2286667	819	Krokinobacter diaphorus 4H-3-7-5 chromosome, complete genome	Cof-like hydrolase	5e-09	60.1
NC_013093:125363:129678	129678	130499	822	Actinosynnema mirum DSM 43827, complete genome	Cof-like hydrolase	8e-09	59.7
NC_017188:2512357:2524377	2524377	2525189	813	Bacillus amyloliquefaciens TA208 chromosome, complete genome	hypothetical protein	1e-08	59.3
NC_017191:2514401:2526421	2526421	2527233	813	Bacillus amyloliquefaciens XH7 chromosome, complete genome	hypothetical protein	1e-08	59.3
NC_012225:1575432:1575432	1575432	1576235	804	Brachyspira hyodysenteriae WA1, complete genome	putative hydrolase	1e-08	59.3
NC_002758:622000:627575	627575	628444	870	Staphylococcus aureus subsp. aureus Mu50, complete genome	hypothetical protein	9e-09	59.3
NC_002745:597947:603329	603329	604198	870	Staphylococcus aureus subsp. aureus N315, complete genome	hypothetical protein	9e-09	59.3
NC_009487:636616:643852	643852	644721	870	Staphylococcus aureus subsp. aureus JH9 chromosome, complete	cof family hydrolase	9e-09	59.3
NC_009632:640973:643728	643728	644597	870	Staphylococcus aureus subsp. aureus JH1 chromosome, complete	cof family hydrolase	9e-09	59.3
NC_013450:557109:564342	564342	565211	870	Staphylococcus aureus subsp. aureus ED98, complete genome	HAD superfamily hydrolase	9e-09	59.3
NC_016928:589223:593304	593304	594173	870	Staphylococcus aureus subsp. aureus M013 chromosome, complete	hydrolase	9e-09	59.3
NC_017343:566000:568857	568857	569726	870	Staphylococcus aureus subsp. aureus ECT-R 2, complete genome	cof-like hydrolase family protein	9e-09	59.3
NC_017351:596000:601395	601395	602264	870	Staphylococcus aureus subsp. aureus 11819-97 chromosome, complete	hypothetical protein	9e-09	59.3
NC_015921:425225:440198	440198	441010	813	Borrelia bissettii DN127 chromosome, complete genome	cof-like hydrolase family protein	1e-08	58.9
NC_015949:2002752:2005073	2005073	2005873	801	Caldicellulosiruptor lactoaceticus 6A chromosome, complete genome	Cof-like hydrolase	1e-08	58.9
NC_017243:517684:537454	537454	538257	804	Brachyspira intermedia PWS/A chromosome, complete genome	hydrolase	1e-08	58.9
NC_016941:574899:582150	582150	583019	870	Staphylococcus aureus subsp. aureus MSHR1132, complete genome	putative haloacid dehalogenase-like hydrolase	1e-08	58.9
NC_013172:783097:786650	786650	787516	867	Brachybacterium faecium DSM 4810, complete genome	HAD-superfamily hydrolase, subfamily IIB	1e-08	58.9
NC_014376:189319:194322	194322	195155	834	Clostridium saccharolyticum WM1 chromosome, complete genome	Cof-like hydrolase	2e-08	58.5
NC_020064:1409596:1436548	1436548	1437348	801	Serratia marcescens FGI94, complete genome	HAD-superfamily hydrolase, subfamily IIB	2e-08	58.5
NC_006156:427358:442357	442357	443196	840	Borrelia garinii PBi chromosome linear, complete sequence	hydrolase	2e-08	58.2
NC_013171:1506500:1507907	1507907	1508734	828	Anaerococcus prevotii DSM 20548, complete genome	Cof-like hydrolase	2e-08	58.2
NC_006582:2205154:2209227	2209227	2209967	741	Bacillus clausii KSM-K16, complete genome	hydrolase, HAD superfamily	2e-08	58.2
NC_014752:617987:617987	617987	618775	789	Neisseria lactamica ST-640, complete genome	hypothetical protein	3e-08	57.8
NC_015968:2110175:2115008	2115008	2115808	801	Enterobacter asburiae LF7a chromosome, complete genome	HAD-superfamily hydrolase	3e-08	57.8
NC_010001:986500:1005379	1005379	1006206	828	Clostridium phytofermentans ISDg, complete genome	Cof-like hydrolase	4e-08	57.4
NC_015224:2701914:2715362	2715362	2716180	819	Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,	putative hydrolase	4e-08	57.4
NC_009725:2517428:2533524	2533524	2534336	813	Bacillus amyloliquefaciens FZB42, complete genome	hypothetical protein	4e-08	57.4
NC_003923:591000:593888	593888	594757	870	Staphylococcus aureus subsp. aureus MW2, complete genome	hypothetical protein	3e-08	57.4
NC_002953:588437:592519	592519	593388	870	Staphylococcus aureus subsp. aureus MSSA476, complete genome	putative haloacid dehalogenase-like hydrolase	3e-08	57.4
NC_014554:337268:351615	351615	352406	792	Lactobacillus plantarum subsp. plantarum ST-III chromosome,	HAD superfamily hydrolase	4e-08	57
NC_004567:343500:359163	359163	359954	792	Lactobacillus plantarum WCFS1, complete genome	hydrolase, HAD superfamily, Cof family	4e-08	57
NC_017353:2353665:2366912	2366912	2367781	870	Staphylococcus lugdunensis N920143, complete genome	putative haloacid dehalogenase-like hydrolase	5e-08	57
NC_013893:2373730:2389398	2389398	2390267	870	Staphylococcus lugdunensis HKU09-01 chromosome, complete genome	Hydrolase (HAD superfamily)	5e-08	57
NC_007793:606500:609260	609260	610129	870	Staphylococcus aureus subsp. aureus USA300, complete genome	hydrolase, haloacid dehalogenase-like family	7e-08	56.6
NC_010079:607000:609802	609802	610671	870	Staphylococcus aureus subsp. aureus USA300_TCH1516, complete	hydrolase	7e-08	56.6
NC_007795:541783:545864	545864	546733	870	Staphylococcus aureus subsp. aureus NCTC 8325, complete genome	hypothetical protein	7e-08	56.6
NC_002951:623461:630693	630693	631562	870	Staphylococcus aureus subsp. aureus COL, complete genome	hydrolase, haloacid dehalogenase-like family	7e-08	56.6
NC_009436:1466580:1469374	1469374	1470186	813	Enterobacter sp. 638, complete genome	cof family hydrolase	7e-08	56.6
NC_009641:597000:599782	599782	600651	870	Staphylococcus aureus subsp. aureus str. Newman chromosome,	hydrolase, haloacid dehalogenase-like protein	7e-08	56.6
NC_016912:541500:545860	545860	546729	870	Staphylococcus aureus subsp. aureus VC40 chromosome, complete	HAD superfamily hydrolase	7e-08	56.6
NC_017347:616000:618799	618799	619668	870	Staphylococcus aureus subsp. aureus T0131 chromosome, complete	Hydrolase, haloacid dehalogenase-like protein	7e-08	56.6
NC_014921:22828:32076	32076	32933	858	Mycoplasma fermentans M64 chromosome, complete genome	hypothetical protein	6e-08	56.6
NC_013192:469771:492134	492134	492925	792	Leptotrichia buccalis DSM 1135, complete genome	Cof-like hydrolase	6e-08	56.6
NC_014650:1410790:1412825	1412825	1413679	855	Geobacillus sp. Y4.1MC1 chromosome, complete genome	Cof-like hydrolase	6e-08	56.6
NC_007633:952728:965268	965268	966110	843	Mycoplasma capricolum subsp. capricolum ATCC 27343, complete	hydrolase, haloacid dehalogenase-like family, putative	6e-08	56.6
NC_014751:946155:958727	958727	959569	843	Mycoplasma leachii PG50 chromosome, complete genome	HAD hydrolase, family IIB	6e-08	56.6
NC_014554:337268:353623	353623	354324	702	Lactobacillus plantarum subsp. plantarum ST-III chromosome,	HAD superfamily hydrolase	9e-08	56.2
NC_004567:343500:361057	361057	361872	816	Lactobacillus plantarum WCFS1, complete genome	hydrolase, HAD superfamily, Cof family	9e-08	56.2
NC_012469:1403412:1403412	1403412	1404812	1401	Streptococcus pneumoniae Taiwan19F-14, complete genome	Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type	8e-08	56.2
NC_015214:1458480:1460388	1460388	1461197	810	Lactobacillus acidophilus 30SC chromosome, complete genome	hypothetical protein	8e-08	56.2
NC_012466:1367099:1367099	1367099	1368499	1401	Streptococcus pneumoniae JJA, complete genome	Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type	8e-08	56.2
NC_011900:1451545:1455235	1455235	1456635	1401	Streptococcus pneumoniae ATCC 700669, complete genome	cyclophilin type peptidyl-prolyl cis-trans isomerase protein	8e-08	56.2
NC_012468:1453763:1453763	1453763	1455163	1401	Streptococcus pneumoniae 70585, complete genome	Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type	8e-08	56.2
NC_008533:1380406:1380406	1380406	1381806	1401	Streptococcus pneumoniae D39, complete genome	Cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type	8e-08	56.2
NC_003098:1372875:1372875	1372875	1374275	1401	Streptococcus pneumoniae R6, complete genome	hypothetical protein	8e-08	56.2
NC_017341:618649:622754	622754	623599	846	Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,	ABC superfamily ATP binding cassette transporter, ABC protein	7e-08	56.2
NC_008262:1721496:1727153	1727153	1727983	831	Clostridium perfringens SM101, complete genome	HAD hydrolase, IIB family	1e-07	55.5
NC_006055:183823:198431	198431	199270	840	Mesoplasma florum L1, complete genome	cof-like hydrolase, HAD-superfamily	1e-07	55.5
NC_012780:284336:308286	308286	309122	837	Eubacterium eligens ATCC 27750 plasmid unnamed, complete sequence	hypothetical protein	2e-07	55.1
NC_017238:427482:442458	442458	443300	843	Borrelia afzelii PKo chromosome, complete genome	cof-like hydrolase family protein	2e-07	55.1
NC_008277:428926:443902	443902	444744	843	Borrelia afzelii PKo, complete genome	hydrolase	2e-07	55.1
NC_007633:446899:450744	450744	451610	867	Mycoplasma capricolum subsp. capricolum ATCC 27343, complete	hydrolase of the HAD superfamily, putative	2e-07	54.7
NC_011071:4235830:4258385	4258385	4259218	834	Stenotrophomonas maltophilia R551-3, complete genome	Cof-like hydrolase	3e-07	54.3
NC_020410:2509057:2537081	2537081	2537866	786	Bacillus amyloliquefaciens subsp. plantarum UCMB5036 complete	Sugar phosphatase SupH	3e-07	54.3
NC_004432:80780:98853	98853	99674	822	Mycoplasma penetrans HF-2, complete genome	predicted haloacid dehalogenase-like hydrolase	3e-07	54.3
NC_020272:1384525:1390597	1390597	1391409	813	Bacillus amyloliquefaciens IT-45, complete genome	hypothetical protein	3e-07	54.3
NC_014652:666227:683550	683550	684350	801	Caldicellulosiruptor hydrothermalis 108 chromosome, complete	cof-like hydrolase	3e-07	54.3
NC_007168:2415361:2435314	2435314	2436183	870	Staphylococcus haemolyticus JCSC1435, complete genome	hypothetical protein	4e-07	53.9
NC_015389:616430:686673	686673	687521	849	Coriobacterium glomerans PW2 chromosome, complete genome	Cof-like hydrolase	6e-07	53.5
NC_009614:769851:784823	784823	785605	783	Bacteroides vulgatus ATCC 8482 chromosome, complete genome	hypothetical protein	6e-07	53.5
NC_014751:449001:452844	452844	453710	867	Mycoplasma leachii PG50 chromosome, complete genome	Cof-like hydrolase	5e-07	53.5
NC_008532:973510:976845	976845	977240	396	Streptococcus thermophilus LMD-9, complete genome		5e-07	53.5
NC_017179:2539031:2566610	2566610	2567431	822	Clostridium difficile BI1, complete genome	hydrolase	8e-07	53.1
NC_013315:2531019:2558598	2558598	2559419	822	Clostridium difficile CD196 chromosome, complete genome	hydrolase	8e-07	53.1
NC_013316:2623199:2639154	2639154	2639975	822	Clostridium difficile R20291, complete genome	putative hydrolase	8e-07	53.1
NC_019978:1816940:1838012	1838012	1838818	807	Halobacteroides halobius DSM 5150, complete genome	HAD-superfamily hydrolase, subfamily IIB	1e-06	52.8
NC_019978:1816940:1838818	1838818	1839627	810	Halobacteroides halobius DSM 5150, complete genome	HAD-superfamily hydrolase, subfamily IIB	1e-06	52.8
NC_014727:889132:890543	890543	891340	798	Lactobacillus delbrueckii subsp. bulgaricus ND02 chromosome,	hydrolase (had superfamily)	9e-07	52.8
NC_009615:1305678:1308655	1308655	1309887	1233	Parabacteroides distasonis ATCC 8503 chromosome, complete genome	haloacid dehalogenase	1e-06	52.4
NC_013416:16493:28156	28156	28974	819	Aggregatibacter actinomycetemcomitans D11S-1, complete genome	phosphatase YbhA	1e-06	52.4
NC_014160:43486:51121	51121	51837	717	Thermosphaera aggregans DSM 11486 chromosome, complete genome	SPP-like hydrolase	1e-06	52
NC_014376:3064787:3084540	3084540	3085331	792	Clostridium saccharolyticum WM1 chromosome, complete genome	Cof-like hydrolase	2e-06	52
NC_016641:3173250:3174692	3174692	3175489	798	Paenibacillus terrae HPL-003 chromosome, complete genome	cof-like hydrolase	2e-06	51.6
NC_012880:135508:138901	138901	139725	825	Dickeya dadantii Ech703, complete genome	Cof-like hydrolase	2e-06	51.6
NC_009009:540992:547564	547564	548961	1398	Streptococcus sanguinis SK36, complete genome	Cof family protein, putative	2e-06	51.6
NC_016633:1130705:1129902	1129902	1130708	807	Sphaerochaeta pleomorpha str. Grapes chromosome, complete genome	HAD-superfamily hydrolase	2e-06	51.6
NC_019978:1816940:1837231	1837231	1838019	789	Halobacteroides halobius DSM 5150, complete genome	HAD-superfamily hydrolase, subfamily IIB	2e-06	51.6
NC_009328:2083386:2094831	2094831	2095679	849	Geobacillus thermodenitrificans NG80-2 chromosome, complete genome	hypothetical protein	2e-06	51.6
NC_014829:4511738:4524197	4524197	4524940	744	Bacillus cellulosilyticus DSM 2522 chromosome, complete genome	Cof-like hydrolase	2e-06	51.6
NC_015875:1926981:1942882	1942882	1944273	1392	Streptococcus pseudopneumoniae IS7493 chromosome, complete genome	putative HAD superfamily hydrolase	3e-06	51.2
NC_006360:518808:517928	517928	518854	927	Mycoplasma hyopneumoniae 232, complete genome	hypothetical protein	3e-06	51.2
NC_015389:809474:814796	814796	815587	792	Coriobacterium glomerans PW2 chromosome, complete genome	HAD-superfamily hydrolase, subfamily IIB	3e-06	51.2
NC_014622:1514416:1515465	1515465	1516265	801	Paenibacillus polymyxa SC2 chromosome, complete genome	cof-like hydrolase	4e-06	50.8
NC_015224:4314116:4319756	4319756	4320553	798	Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,	hypothetical protein	4e-06	50.8
NC_008800:4389687:4396053	4396053	4396757	705	Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,	hypothetical protein	3e-06	50.8
NC_015638:23654:40522	40522	41328	807	Lacinutrix sp. 5H-3-7-4 chromosome, complete genome	Cof-like hydrolase	3e-06	50.8
NC_016513:317197:330470	330470	331288	819	Aggregatibacter actinomycetemcomitans ANH9381 chromosome, complete	phosphatase YbhA	5e-06	50.4
NC_014483:1376500:1377659	1377659	1378459	801	Paenibacillus polymyxa E681 chromosome, complete genome	hypothetical protein	5e-06	50.4
NC_012947:2898179:2912335	2912335	2913150	816	Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, complete	Cof-like hydrolase	6e-06	50.1
NC_011601:846358:849698	849698	850513	816	Escherichia coli O127:H6 str. E2348/69 chromosome, complete genome	hypothetical protein	7e-06	49.7

*Host Accession, e.g.* NC_0123..**	*Host Description, e.g.* Clostri...**

*Host Lineage, e.g.* archae, Proteo, Firmi...**

*Host Information, e.g.* soil, Thermo, Russia**