Pre_GI Gene

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Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:2321999 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
232199923232071209transporter major facilitator family proteinQuickGO ontologyBLASTP
232325623254152160NaH antiporterQuickGO ontologyBLASTP
23257642326321558transcription factor WhiBQuickGO ontologyBLASTP
23263942327149756HAD superfamily hydrolaseQuickGO ontologyBLASTP
23272752327424150thiazolylpeptide-type bacteriocinQuickGO ontologyBLASTP
23275722328480909ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
23284702329204735ABC transporter-associated permeaseQuickGO ontologyBLASTP
23292012329398198hypothetical proteinBLASTP
23295342330118585cupin domain proteinQuickGO ontologyBLASTP
23301312330871741B34 domain-containing proteinQuickGO ontologyBLASTP
233128223325561275hypothetical proteinBLASTP
233270423341911488cytosinepurines uracil thiamine allantoin permeaseQuickGO ontologyBLASTP
23342452334547303Ferredoxin-like protein fixXQuickGO ontologyBLASTP
233454723359171371FAD dependent oxidoreductaseQuickGO ontologyBLASTP
23359142336792879electron transfer flavoprotein FAD-binding domain proteinQuickGO ontologyBLASTP
23368252337586762electron transfer flavoprotein domain proteinQuickGO ontologyBLASTP
233769523388611167CoA-transferase family IIIQuickGO ontologyBLASTP
233889923400471149acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
23402732341037765IclR family transcriptional regulatorQuickGO ontologyBLASTP
234247323437471275seryl-tRNA synthetaseQuickGO ontologyBLASTP
23438342344652819hypothetical proteinBLASTP
23449232345120198prephenate dehydrataseQuickGO ontologyBLASTP
23453672346098732leucylphenylalanyl-tRNA--protein transferaseQuickGO ontologyBLASTP
23465392346799261hypothetical proteinBLASTP
23467622346896135hypothetical proteinBLASTP
23469422347316375siderophore-interacting proteinQuickGO ontologyBLASTP
23473692348223855undecaprenyl pyrophosphate phosphataseQuickGO ontologyBLASTP
23484352348953519ferritin-like proteinQuickGO ontologyBLASTP