Pre_GI Gene

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Host: NC_014039 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014039:2320307 Propionibacterium acnes SK137 chromosome, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
232030723224842178transporter CPA2 familyQuickGO ontologyBLASTP
23228072323373567transcription factor WhiBQuickGO ontologyBLASTP
23234282324201774HAD hydrolase family IIBQuickGO ontologyBLASTP
23243272324476150thiazolylpeptide-type bacteriocinQuickGO ontologyBLASTP
23246362325532897ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
23255222326256735ABC-2 type transporterQuickGO ontologyBLASTP
23263142327180867cupin domain proteinQuickGO ontologyBLASTP
23271932327933741B34 domain proteinQuickGO ontologyBLASTP
232834423296241281hypothetical proteinBLASTP
232977223312591488permease cytosinepurine uracil thiamine allantoin familyQuickGO ontologyBLASTP
233161523329851371FAD dependent oxidoreductaseQuickGO ontologyBLASTP
23329822333860879electron transfer flavoprotein FAD-binding domain proteinQuickGO ontologyBLASTP
23338932334654762electron transfer flavoprotein domain proteinQuickGO ontologyBLASTP
233476323359291167CoA-transferase family IIIQuickGO ontologyBLASTP
233596723371151149acyl-CoA dehydrogenase C-terminal domain proteinQuickGO ontologyBLASTP
23373412338105765transcriptional regulator IclR family C-terminal domain proteinQuickGO ontologyBLASTP
23382192338734516hypothetical proteinBLASTP
23387562339544789hypothetical proteinBLASTP
233954123408151275serine--tRNA ligaseQuickGO ontologyBLASTP
23409022341720819hypothetical proteinBLASTP
23424352343166732leucyltransferaseQuickGO ontologyBLASTP
23436072343867261hypothetical proteinBLASTP
23438302343964135hypothetical proteinBLASTP
23440102344384375siderophore-interacting proteinQuickGO ontologyBLASTP
23444372345291855undecaprenyl-diphosphatase UppPQuickGO ontologyBLASTP
23455032346021519ferritin-like proteinQuickGO ontologyBLASTP
23460692346263195hypothetical proteinBLASTP