Pre_GI Gene

Some Help

Host: NC_016512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016512:2322598 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
232259823247572160NaH antiporterQuickGO ontologyBLASTP
23251062325663558transcription factor WhiBQuickGO ontologyBLASTP
23257182326491774HAD superfamily hydrolaseQuickGO ontologyBLASTP
23266172326766150thiazolylpeptide-type bacteriocinQuickGO ontologyBLASTP
23269142327822909ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
23278122328546735ABC transporter-associated permeaseQuickGO ontologyBLASTP
23285432328740198hypothetical proteinBLASTP
23288672329460594cupin domain proteinQuickGO ontologyBLASTP
23294732330213741B34 domain-containing proteinQuickGO ontologyBLASTP
233062423318981275hypothetical proteinBLASTP
233204623335331488cytosinepurines uracil thiamine allantoin permeaseQuickGO ontologyBLASTP
23335872333889303Ferredoxin-like protein fixXQuickGO ontologyBLASTP
233388923352591371FAD dependent oxidoreductaseQuickGO ontologyBLASTP
23352562336134879electron transfer flavoprotein FAD-binding domain proteinQuickGO ontologyBLASTP
23361672336928762electron transfer flavoprotein domain proteinQuickGO ontologyBLASTP
233703723382031167CoA-transferase family IIIQuickGO ontologyBLASTP
233824123393891149acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
23396152340379765IclR family transcriptional regulatorQuickGO ontologyBLASTP
234181523430891275seryl-tRNA synthetaseQuickGO ontologyBLASTP
23431762343994819hypothetical proteinBLASTP
23442652344462198prephenate dehydrataseQuickGO ontologyBLASTP
23447092345440732leucylphenylalanyl-tRNA--protein transferaseQuickGO ontologyBLASTP
23458812346141261hypothetical proteinBLASTP
23461042346238135hypothetical proteinBLASTP
23462842346658375siderophore-interacting proteinQuickGO ontologyBLASTP
23467112347565855undecaprenyl pyrophosphate phosphataseQuickGO ontologyBLASTP
23477772348295519ferritin-like proteinQuickGO ontologyBLASTP
23483072348537231hypothetical proteinBLASTP