Pre_GI Gene

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Host: NC_017316 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017316:2466244 Enterococcus faecalis OG1RF chromosome, complete genome

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
24662442466807564peptide deformylaseQuickGO ontologyBLASTP
24668542467633780hydrolaseQuickGO ontologyBLASTP
24676402468341702DNA alkylation repair proteinQuickGO ontologyBLASTP
24683662469169804formatenitrite transporterQuickGO ontologyBLASTP
2469494247010561230S ribosomal protein S4QuickGO ontologyBLASTP
24702652470813549BioY family proteinQuickGO ontologyBLASTP
24708752471411537signal peptidase I LepBQuickGO ontologyBLASTP
247146624753683903hypothetical proteinBLASTP
24756402475765126hypothetical proteinBLASTP
247586224797763915hypothetical proteinBLASTP
24797632480125363cell wall surface anchor family proteinQuickGO ontologyBLASTP
24804912481102612hypothetical proteinBLASTP
24811372481694558GNAT family acetyltransferaseQuickGO ontologyBLASTP
248178024830001221tripeptide aminopeptidaseQuickGO ontologyBLASTP
248302224846651644oligopeptide ABC superfamily ATP binding cassette transporter binding proteinQuickGO ontologyBLASTP
24851092486062954ferric Fe3 ABC superfamily ATP binding cassette transporter binding proteinQuickGO ontologyBLASTP
24861012486856756ABC superfamily ATP binding cassette transporter ABC proteinQuickGO ontologyBLASTP
24868532487818966ferric Fe3 ABC superfamily ATP binding cassette transporter membrane proteinQuickGO ontologyBLASTP
24878152488762948ABC superfamily ATP binding cassette transporter membrane proteinQuickGO ontologyBLASTP