Pre_GI Gene

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Host: NC_016516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016516:2314115 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
231411523162742160NaH antiporterQuickGO ontologyBLASTP
23166232317180558transcription factor WhiBQuickGO ontologyBLASTP
23172532318008756HAD superfamily hydrolaseQuickGO ontologyBLASTP
23184312319339909ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
23193292320063735ABC transporter-associated permeaseQuickGO ontologyBLASTP
23203922320976585cupin domain proteinQuickGO ontologyBLASTP
23209892321729741B34 domain-containing proteinQuickGO ontologyBLASTP
232214023234141275hypothetical proteinBLASTP
232356223250461485cytosinepurines uracil thiamine allantoin permeaseQuickGO ontologyBLASTP
23251032325405303Ferredoxin-like protein fixXQuickGO ontologyBLASTP
232540523267751371FAD dependent oxidoreductaseQuickGO ontologyBLASTP
23267722327650879electron transfer flavoprotein FAD-binding domain proteinQuickGO ontologyBLASTP
23276832328444762electron transfer flavoprotein domain proteinQuickGO ontologyBLASTP
232855323297191167CoA-transferase family IIIQuickGO ontologyBLASTP
232975723309051149acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
23311312331895765IclR family transcriptional regulatorQuickGO ontologyBLASTP
23320092332449441hypothetical proteinBLASTP
23325472333335789hypothetical proteinBLASTP
233333223346061275seryl-tRNA synthetaseQuickGO ontologyBLASTP
23346932335511819hypothetical proteinBLASTP
23357822335979198prephenate dehydrataseQuickGO ontologyBLASTP
23362262336957732leucylphenylalanyl-tRNA--protein transferaseQuickGO ontologyBLASTP
23373982337658261hypothetical proteinBLASTP
23376212337755135hypothetical proteinBLASTP
23378012338175375siderophore-interacting proteinQuickGO ontologyBLASTP
23382282339082855undecaprenyl pyrophosphate phosphataseQuickGO ontologyBLASTP
23392942339812519ferritin-like proteinQuickGO ontologyBLASTP
23398242340054231hypothetical proteinBLASTP