Pre_GI Gene

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Host: NC_006085 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006085:2384892 Propionibacterium acnes KPA171202, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
238489223870512160putative NaH antiporterQuickGO ontologyBLASTP
23874002387957558hypothetical proteinBLASTP
23880122388785774hydrolase HAD superfamilyQuickGO ontologyBLASTP
23891752389531357ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
23899522390839888putative ABC transporter-associated permeaseQuickGO ontologyBLASTP
23908972391763867putative transcriptional regulatorQuickGO ontologyBLASTP
23917762392516741hypothetical proteinBLASTP
239280323941941392hypothetical protein putative adhesion or S-layer proteinQuickGO ontologyBLASTP
239434223958291488purine cytosine permease-like proteinQuickGO ontologyBLASTP
239618523975341350putative electron transfer flavoprotein-quinone oxidoreductase FixC proteinQuickGO ontologyBLASTP
23975522398430879putative electron transfer flavoprotein carnitine metabolism FixB proteinQuickGO ontologyBLASTP
23984632399224762putative electron transfer flavoprotein FixA proteinQuickGO ontologyBLASTP
239933324004991167putative L-carnitine dehydrataseQuickGO ontologyBLASTP
240053724016851149acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
24019112402675765transcriptional regulator IclR familyQuickGO ontologyBLASTP
240278924041141326hypothetical proteinBLASTP
240411124053851275seryl-tRNA synthetaseQuickGO ontologyBLASTP
24054722406290819conserved protein PRC-barrel domainQuickGO ontologyBLASTP
24070052407736732leucylphenylalanyl-tRNA-protein transferaseQuickGO ontologyBLASTP
24081772408437261hypothetical proteinBLASTP
24085802408954375siderophore-interacting protein fragmentQuickGO ontologyBLASTP
24090072409861855undecaprenyl pyrophosphate phosphataseQuickGO ontologyBLASTP
24100732410591519ferritinQuickGO ontologyBLASTP
24109222411560639hypothetical protein