Pre_GI: BLASTP Hits

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Query: NC_003143:2849377:2852232 Yersinia pestis CO92, complete genome

Start: 2852232, End: 2852768, Length: 537

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a recent Orientalis subtype isolated in the USA from a patient who died of pneumonic plague after acquiring the disease from an infected cat. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1521276:154048415404841541020537Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative thermosensitive gluconokinase1e-87322
NC_010465:1724000:174224517422451742781537Yersinia pseudotuberculosis YPIII, complete genomecarbohydrate kinase, thermoresistant glucokinase family1e-87322
NC_004088:1801819:181991518199151820451537Yersinia pestis KIM, complete genomegluconokinase 11e-87322
NC_005810:2613456:261631126163112616847537Yersinia pestis biovar Microtus str. 91001, complete genomeputative thermosensitive gluconokinase1e-87322
NC_006155:3040769:304362530436253044161537Yersinia pseudotuberculosis IP 32953, complete genomeputative thermosensitive gluconokinase1e-87322
NC_008149:2411161:241401624140162414552537Yersinia pestis Nepal516, complete genomethermosensitive gluconokinase1e-87322
NC_010159:1861465:186432018643201864856537Yersinia pestis Angola, complete genomethermosensitive gluconokinase1e-87322
NC_010634:2960000:296153329615332962069537Yersinia pseudotuberculosis PB1/+, complete genomecarbohydrate kinase1e-87322
NC_017154:3139614:315720331572033157739537Yersinia pestis D106004 chromosome, complete genomeputative thermosensitive gluconokinase1e-87322
NC_017160:2740870:275681227568122757348537Yersinia pestis D182038 chromosome, complete genomeputative thermosensitive gluconokinase1e-87322
NC_017168:2892000:290966829096682910204537Yersinia pestis A1122 chromosome, complete genomeputative thermosensitive gluconokinase1e-87322
NC_009708:1694685:171084517108451711381537Yersinia pseudotuberculosis IP 31758 chromosome, complete genomethermosensitive gluconokinase2e-84311
NC_008800:1497746:151699015169901517520531Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,putative thermosensitive gluconokinase8e-78289
NC_012912:242709:259633259633260151519Dickeya zeae Ech1591, complete genomecarbohydrate kinase, thermoresistant glucokinase family4e-55213
NC_012691:241404:255595255595256122528Tolumonas auensis DSM 9187, complete genomecarbohydrate kinase, thermoresistant glucokinase family2e-51201
NC_010519:796229:799663799663800181519Haemophilus somnus 2336 chromosome, complete genomecarbohydrate kinase2e-51201
NC_008309:385592:389391389391389909519Haemophilus somnus 129PT, complete genomegluconokinase (gluconate kinase)2e-51201
NC_012967:4473368:447785144778514478414564Escherichia coli B str. REL606 chromosome, complete genomeD-gluconate kinase4e-50197
NC_012947:3917619:393569439356943936257564Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completeD-gluconate kinase4e-50197
NC_011750:4947500:494876749487674949330564Escherichia coli IAI39 chromosome, complete genomeD-gluconate kinase4e-50197
NC_008563:4905186:491127849112784911841564Escherichia coli APEC O1, complete genomethermosensitive gluconokinase6e-50196
NC_009800:4529504:453075245307524531315564Escherichia coli HS, complete genomethermosensitive gluconokinase2e-49194
CP002185:4750571:475260747526074753170564Escherichia coli W, complete genomeD-gluconate kinase, thermosensitive2e-49194
NC_006905:4638707:464318746431874643717531Salmonella enterica subsp. enterica serovar Choleraesuis strD-gluconate kinase, thermosensitive5e-49193
NC_011080:4703266:470774647077464708276531Salmonella enterica subsp. enterica serovar Newport str. SL254,shikimate kinase5e-49193
NC_012125:4716000:472050147205014721031531Salmonella enterica subsp. enterica serovar Paratyphi C strainD-gluconate kinase5e-49193
NC_011205:4718239:472165747216574722187531Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853D-gluconate kinase5e-49193
NC_011274:4538722:454214045421404542670531Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91D-gluconate kinase5e-49193
NC_011294:4560902:456432045643204564850531Salmonella enterica subsp. enterica serovar Enteritidis strD-gluconate kinase5e-49193
NC_016831:4517850:452146845214684521998531Salmonella enterica subsp. enterica serovar Gallinarum/pullorumthermosensitive gluconokinase (gluconate kinase 1)5e-49193
NC_010102:4745949:474594947459494746479531Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein5e-49193
NC_010067:3056774:307737630773763077924549Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein4e-45180
NC_012214:3750649:377732737773273777875549Erwinia pyrifoliae Ep1/96, complete genomeThermoresistant gluconokinase (Gluconate kinase 2)3e-41167
NC_020126:735259:764774764774765259486Myxococcus stipitatus DSM 14675, complete genomethermosensitive gluconokinase1e-31135
NC_016801:170876:199017199017199520504Corynebacterium diphtheriae C7 (beta) chromosome, complete genomeputative gluconokinase3e-31134
NC_007645:3688000:369127336912733691857585Hahella chejuensis KCTC 2396, complete genomeGluconate kinase1e-29129
NC_011992:1968258:199796219979621998510549Acidovorax ebreus TPSY, complete genomecarbohydrate kinase, thermoresistant glucokinase family5e-29127
NC_016027:1401500:140462314046231405192570Gluconacetobacter xylinus NBRC 3288, complete genomegluconokinase7e-29126
NC_013174:2564979:257815025781502578680531Jonesia denitrificans DSM 20603, complete genomecarbohydrate kinase, thermoresistant glucokinase family9e-29126
NC_007650:420745:428980428980429486507Burkholderia thailandensis E264 chromosome II, complete sequencethermoresistant gluconokinase1e-28125
NC_007164:453743:454707454707455258552Corynebacterium jeikeium K411, complete genomeputative gluconokinase5e-1270.5