Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:4703266 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
47032664704264999HTH-type transcriptional regulator IdnRQuickGO ontologyBLASTP
470432847057191392transporter gluconateH symporter GntP familyQuickGO ontologyBLASTP
47057094706473765gluconate 5-dehydrogenaseQuickGO ontologyBLASTP
470649847075291032L-idonate 5-dehydrogenaseQuickGO ontologyBLASTP
47077464708276531shikimate kinaseQuickGO ontologyBLASTP
470830447093231020hypothetical proteinBLASTP
470979347110581266integraseQuickGO ontologyBLASTP
471110847136572550putative deaddeah box helicase domain proteinQuickGO ontologyBLASTP
471364147146781038hypothetical proteinBLASTP
47151094715231123putative Ogr family transcription activatorQuickGO ontologyBLASTP
47153834715937555putative polarity suppression protein encoded in CP-933IQuickGO ontologyBLASTP
47159344716686753putative capsid morphogenesis protein encoded in CP-933IQuickGO ontologyBLASTP
47175994717859261phage transcriptional regulator AlpAQuickGO ontologyBLASTP
47179084718033126hypothetical proteinBLASTP
47182134718404192phage immunity repressor proteinQuickGO ontologyBLASTP
47184044718625222hypothetical proteinBLASTP
47186254718948324hypothetical proteinBLASTP
471896347212932331bacteriophage P4 DNA primaseQuickGO ontologyBLASTP
47232384723954717hypothetical proteinBLASTP
47240524724183132hypothetical protein
472451447261391626putative SAM-dependent methyltransferaseQuickGO ontologyBLASTP
47261504726407258protein YjhXQuickGO ontologyBLASTP
47266504726763114hypothetical proteinBLASTP
47268944727502609hypothetical proteinBLASTP
47278544728765912putative cytoplasmic proteinQuickGO ontologyBLASTP