Query: NC_003366:2057656 Clostridium perfringens str. 13, complete genome
Start: 2057656, End: 2082099, Length: 24444
Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: This strain is a type A isolate from the soil. It can establish gas gangrene in a murine experimental model. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_008262:1950205* | 1950205 | 1969678 | 19474 | Clostridium perfringens SM101, complete genome | 0 | 10000 | BLASTN svg | BLASTP svg |
NC_021182:2422226* | 2422226 | 2447353 | 25128 | Clostridium pasteurianum BC1, complete genome | 1e-67 | 266 | BLASTN svg | BLASTP svg |
NC_008593:1461771* | 1461771 | 1484982 | 23212 | Clostridium novyi NT, complete genome | 2e-65 | 258 | BLASTN svg | BLASTP svg |
NC_012563:2680246* | 2680246 | 2720775 | 40530 | Clostridium botulinum A2 str. Kyoto, complete genome | 1e-42 | 182 | BLASTN svg | BLASTP svg |
NC_010516:2511035* | 2511035 | 2545889 | 34855 | Clostridium botulinum B1 str. Okra, complete genome | 5e-42 | 180 | BLASTN svg | BLASTP svg |
NC_014328:1307490* | 1307490 | 1331216 | 23727 | Clostridium ljungdahlii ATCC 49587 chromosome, complete genome | 1e-33 | 153 | BLASTN svg | BLASTP svg |
NC_010520:2585014* | 2585014 | 2620419 | 35406 | Clostridium botulinum A3 str. Loch Maree, complete genome | 6e-32 | 147 | BLASTN svg | BLASTP svg |
NC_010674:2435241 | 2435241 | 2459364 | 24124 | Clostridium botulinum B str. Eklund 17B, complete genome | 1e-26 | 129 | BLASTN svg | BLASTP svg |
NC_015687:1811573* | 1811573 | 1834638 | 23066 | Clostridium acetobutylicum DSM 1731 chromosome, complete genome | 2e-25 | 125 | BLASTN svg | BLASTP svg |
NC_003030:1811820* | 1811820 | 1835053 | 23234 | Clostridium acetobutylicum ATCC 824, complete genome | 2e-25 | 125 | BLASTN svg | BLASTP svg |
NC_014964:1169925 | 1169925 | 1188604 | 18680 | Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete | 9e-25 | 123 | BLASTN svg | BLASTP svg |
NC_014538:1311500* | 1311500 | 1335397 | 23898 | Thermoanaerobacter sp. X513 chromosome, complete genome | 9e-25 | 123 | BLASTN svg | BLASTP svg |
NC_019978:1244000 | 1244000 | 1265707 | 21708 | Halobacteroides halobius DSM 5150, complete genome | 2e-19 | 105 | BLASTN svg | BLASTP svg |
NC_014721:1777644* | 1777644 | 1816005 | 38362 | Caldicellulosiruptor kristjanssonii 177R1B chromosome, complete | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_015949:1180755* | 1180755 | 1216930 | 36176 | Caldicellulosiruptor lactoaceticus 6A chromosome, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_012034:1783912* | 1783912 | 1823670 | 39759 | Anaerocellum thermophilum DSM 6725, complete genome | 8e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_014720:1161841* | 1161841 | 1181484 | 19644 | Caldicellulosiruptor kronotskyensis 2002 chromosome, complete | 5e-11 | 77.8 | BLASTN svg | BLASTP svg |
NC_014652:1032711* | 1032711 | 1073951 | 41241 | Caldicellulosiruptor hydrothermalis 108 chromosome, complete | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_011772:4321117* | 4321117 | 4339226 | 18110 | Bacillus cereus G9842, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_010520:2171584 | 2171584 | 2194490 | 22907 | Clostridium botulinum A3 str. Loch Maree, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_014392:969498* | 969498 | 1009150 | 39653 | Caldicellulosiruptor obsidiansis OB47 chromosome, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_003454:1346500* | 1346500 | 1365862 | 19363 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014150:1304573* | 1304573 | 1324439 | 19867 | Brachyspira murdochii DSM 12563 chromosome, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014657:1518721* | 1518721 | 1540348 | 21628 | Caldicellulosiruptor owensensis OL chromosome, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_016012:805680* | 805680 | 827841 | 22162 | Candidatus Arthromitus sp. SFB-rat-Yit, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_014166:401815* | 401815 | 426117 | 24303 | Arcobacter nitrofigilis DSM 7299 chromosome, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_012563:2203037 | 2203037 | 2224765 | 21729 | Clostridium botulinum A2 str. Kyoto, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_010516:2064027 | 2064027 | 2084981 | 20955 | Clostridium botulinum B1 str. Okra, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_007530:4176462* | 4176462 | 4200418 | 23957 | Bacillus anthracis str. 'Ames Ancestor', complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |