Pre_GI: BLASTN Hits

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Query: NC_015848:483500 Mycobacterium canettii CIPT 140010059, complete genome

Start: 483500, End: 509988, Length: 26489

Host Lineage: Mycobacterium canettii; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: The Republic of Djibouti, Africa appears to be an exceptional place in terms of tuberculosis (TB) caused by Mycobacterium canettii, a highly unusual tubercle bacillus with unusual smooth colony morphology (STB) related to the M. tuberculosis complex (MTBC). M. canettii was first isolated from a 20-year-old French farmer suffering from pulmonary tuberculosis by G. Canetti in 1969. Since then, this strain has been isolated on rare occasions from patients who lived or were presumably infected in East Africa. It tends to preferentially affect children and foreigners in the Horn of Africa. M. canettii, a possible ancestor of the MTBC, is found almost exclusively in the Horn of Africa where TB is thought to have emerged about 40 000 years ago, coinciding with the expansion of human population out of Africa. The geographical restriction of M. canettii isolates and contrasting genetic diversity are characteristics compatible with a non-human reservoir. With the larger pan-genome reflecting the ancestral, wider gene pool of tubercle bacilli, their lower virulence and faster growth, especially at temperatures below 37 degrees C, plausibly reflecting broader environmental adaptability, STB strains might thus come nearer to the as-yet-unknown missing link between the obligate pathogen M. tuberculosis and environmental mycobacteria (adapted from PMIDs 20831613 and 23291586). Mycobacteria have an unusual outer membrane approximately 8nm thick, despite being considered Gram-positive. The outer membrane and the mycolic acid-arabinoglactan-peptidoglycan polymer form the cell wall, which constitutes an efficient permeability barrier in conjunction with the cell inner membrane.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_019950:48188148188150600724127Mycobacterium canettii CIPT 140060008 complete genome024870BLASTN svgBLASTP svg
NC_009525:47709347709350092923837Mycobacterium tuberculosis H37Ra, complete genome024450BLASTN svgBLASTP svg
NC_000962:47581647581649961923804Mycobacterium tuberculosis H37Rv, complete genome024450BLASTN svgBLASTP svg
NC_008769:50700050700053043423435Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome024410BLASTN svgBLASTP svg
NC_002945:47683547683550063823804Mycobacterium bovis AF2122/97, complete genome024410BLASTN svgBLASTP svg
NC_009565:47950047950050278923290Mycobacterium tuberculosis F11, complete genome024240BLASTN svgBLASTP svg
NC_012207:47750047750050076723268Mycobacterium bovis BCG str. Tokyo 172, complete genome024150BLASTN svgBLASTP svg
NC_002755:47287247287249645723586Mycobacterium tuberculosis CDC1551, complete genome013730BLASTN svgBLASTP svg
NC_010612:83564883564886299927352Mycobacterium marinum M, complete genome01487BLASTN svgBLASTP svg
NC_011896:36344836344838894925502Mycobacterium leprae Br4923, complete genome01140BLASTN svgBLASTP svg
NC_002677:36343236343238893225501Mycobacterium leprae TN, complete genome01140BLASTN svgBLASTP svg
NC_011896:332939*33293935403321095Mycobacterium leprae Br4923, complete genome4e-163583BLASTN svgBLASTP svg
NC_002677:332923*33292335401721095Mycobacterium leprae TN, complete genome4e-163583BLASTN svgBLASTP svg
NC_012522:2031786*2031786206157229787Rhodococcus opacus B4, complete genome8e-44186BLASTN svgBLASTP svg
NC_013159:1807599*1807599183475127153Saccharomonospora viridis DSM 43017, complete genome2e-38168BLASTN svgBLASTP svg
NC_008268:2313583*2313583234448830906Rhodococcus sp. RHA1, complete genome2e-29139BLASTN svgBLASTP svg
NC_008271:35909359096246126553Rhodococcus sp. RHA1 plasmid pRHL3, complete sequence2e-29139BLASTN svgBLASTP svg
NC_000962:32884643288464331029721834Mycobacterium tuberculosis H37Rv, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_002755:32827853282785330371920935Mycobacterium tuberculosis CDC1551, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_002945:32462783246278326609919822Mycobacterium bovis AF2122/97, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_008769:32424533242453326356021108Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_009525:33004563300456332228921834Mycobacterium tuberculosis H37Ra, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_009565:32999373299937332177021834Mycobacterium tuberculosis F11, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_012207:32374403237440325728519846Mycobacterium bovis BCG str. Tokyo 172, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_015848:33437313343731336691823188Mycobacterium canettii CIPT 140010059, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_015957:61193466119346619590076555Streptomyces violaceusniger Tu 4113 chromosome, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_019950:33064193306419333122724809Mycobacterium canettii CIPT 140060008 complete genome5e-1487.7BLASTN svgBLASTP svg
NC_010572:73042907304290735268448395Streptomyces griseus subsp. griseus NBRC 13350, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_000962:18708421870842189534224501Mycobacterium tuberculosis H37Rv, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_002755:18596301859630187892619297Mycobacterium tuberculosis CDC1551, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_002945:18562281856228188073824511Mycobacterium bovis AF2122/97, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_008769:18761091876109190061624508Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_009525:18723601872360189686024501Mycobacterium tuberculosis H37Ra, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_009565:18662141866214189074224529Mycobacterium tuberculosis F11, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_009921:57874375787437580894021504Frankia sp. EAN1pec, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_012207:18480911848091186924521155Mycobacterium bovis BCG str. Tokyo 172, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_015848:18966601896660192209125432Mycobacterium canettii CIPT 140010059, complete genome3e-1281.8BLASTN svgBLASTP svg
NC_019950:18708631870863189629425432Mycobacterium canettii CIPT 140060008 complete genome3e-1281.8BLASTN svgBLASTP svg
NC_015953:58657335865733590682141089Streptomyces sp. SirexAA-E chromosome, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_003155:11378171137817120257364757Streptomyces avermitilis MA-4680, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010612:103081*10308113565632576Mycobacterium marinum M, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010694:13242501324250134559221343Erwinia tasmaniensis, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_020133:77341773419927021930Mycobacterium liflandii 128FXT, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_013947:44133824413382443709923718Stackebrandtia nassauensis DSM 44728 chromosome, complete genome8e-1073.8BLASTN svgBLASTP svg
NC_008271:14084614084616654625701Rhodococcus sp. RHA1 plasmid pRHL3, complete sequence8e-1073.8BLASTN svgBLASTP svg
NC_015957:45464034546403458592939527Streptomyces violaceusniger Tu 4113 chromosome, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_002944:18814051881405190464023236Mycobacterium avium subsp. paratuberculosis K-10, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_009142:45718894571889461144339555Saccharopolyspora erythraea NRRL 2338, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_010397:43875004387500440592818429Mycobacterium abscessus chromosome Chromosome, complete sequence1e-0869.9BLASTN svgBLASTP svg
NC_013093:30684863068486311387545390Actinosynnema mirum DSM 43827, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014391:26513152651315269455543241Micromonospora aurantiaca ATCC 27029 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_015957:42928194292819431625023432Streptomyces violaceusniger Tu 4113 chromosome, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_020133:2886541*2886541291380027260Mycobacterium liflandii 128FXT, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_013595:9994000*99940001001201918020Streptosporangium roseum DSM 43021, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_002516:89100089100091357122572Pseudomonas aeruginosa PAO1, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_008611:2615204*2615204263604620843Mycobacterium ulcerans Agy99, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_010612:3745332*3745332378131835987Mycobacterium marinum M, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_011770:49241274924127497209947973Pseudomonas aeruginosa LESB58, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_015957:45255804525580455677331194Streptomyces violaceusniger Tu 4113 chromosome, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_002677:17160001716000173800622007Mycobacterium leprae TN, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_002944:12854361285436132132435889Mycobacterium avium subsp. paratuberculosis K-10, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_011896:17160001716000173793921940Mycobacterium leprae Br4923, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_015957:60295426029542605506325522Streptomyces violaceusniger Tu 4113 chromosome, complete genome8e-0763.9BLASTN svgBLASTP svg
NC_018681:1021063*1021063104680525743Nocardia brasiliensis ATCC 700358 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_015859:10691161069116109541926304Corynebacterium variabile DSM 44702 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_014831:86661486661489112124508Thermaerobacter marianensis DSM 12885 chromosome, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_013440:39770973977097405558678490Haliangium ochraceum DSM 14365, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_009565:2306574*2306574233169725124Mycobacterium tuberculosis F11, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_008596:421882*42188246586743986Mycobacterium smegmatis str. MC2 155, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_008595:66150766150768418722681Mycobacterium avium 104, complete genome3e-0661.9BLASTN svgBLASTP svg