Pre_GI Gene

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Host: NC_002945 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002945:476835 Mycobacterium bovis AF2122/97, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
47683547720336913E12 repeat family proteinQuickGO ontologyBLASTP
477698478339642hypothetical proteinBLASTP
4783464795751230lipoprotein LpqKQuickGO ontologyBLASTP
4795854807721188acyl-CoA dehydrogenase FADE7QuickGO ontologyBLASTP
480808481179372transmembrane proteinQuickGO ontologyBLASTP
4813744824771104transmembrane transport protein MmpL1BQuickGO ontologyBLASTP
4824744842491776transmembrane transport protein MmpL1AQuickGO ontologyBLASTP
484246484674429membrane proteinQuickGO ontologyBLASTP
4849954867521758acyl-CoA synthetaseQuickGO ontologyBLASTP
4867494881311383polyketide synthaseQuickGO ontologyBLASTP
4881184909582841polyketide synthaseQuickGO ontologyBLASTP
490906491724819beta lactamase like proteinQuickGO ontologyBLASTP
4918024928121011F420-dependent glucose-6-phosphate dehydrogenaseQuickGO ontologyBLASTP
4928054948772073phosphate acetyltransferaseQuickGO ontologyBLASTP
4948704960271158acetate kinaseQuickGO ontologyBLASTP
4960814983332253serinethreonine-protein kinase PKNG protein kinase G STPK GQuickGO ontologyBLASTP
498333499319987glutamine-binding lipoproteinQuickGO ontologyBLASTP
4993195006381320hypothetical proteinBLASTP